Ultrafiltration (renal)

Jump to navigation Jump to search

WikiDoc Resources for Ultrafiltration (renal)


Most recent articles on Ultrafiltration (renal)

Most cited articles on Ultrafiltration (renal)

Review articles on Ultrafiltration (renal)

Articles on Ultrafiltration (renal) in N Eng J Med, Lancet, BMJ


Powerpoint slides on Ultrafiltration (renal)

Images of Ultrafiltration (renal)

Photos of Ultrafiltration (renal)

Podcasts & MP3s on Ultrafiltration (renal)

Videos on Ultrafiltration (renal)

Evidence Based Medicine

Cochrane Collaboration on Ultrafiltration (renal)

Bandolier on Ultrafiltration (renal)

TRIP on Ultrafiltration (renal)

Clinical Trials

Ongoing Trials on Ultrafiltration (renal) at Clinical Trials.gov

Trial results on Ultrafiltration (renal)

Clinical Trials on Ultrafiltration (renal) at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Ultrafiltration (renal)

NICE Guidance on Ultrafiltration (renal)


FDA on Ultrafiltration (renal)

CDC on Ultrafiltration (renal)


Books on Ultrafiltration (renal)


Ultrafiltration (renal) in the news

Be alerted to news on Ultrafiltration (renal)

News trends on Ultrafiltration (renal)


Blogs on Ultrafiltration (renal)


Definitions of Ultrafiltration (renal)

Patient Resources / Community

Patient resources on Ultrafiltration (renal)

Discussion groups on Ultrafiltration (renal)

Patient Handouts on Ultrafiltration (renal)

Directions to Hospitals Treating Ultrafiltration (renal)

Risk calculators and risk factors for Ultrafiltration (renal)

Healthcare Provider Resources

Symptoms of Ultrafiltration (renal)

Causes & Risk Factors for Ultrafiltration (renal)

Diagnostic studies for Ultrafiltration (renal)

Treatment of Ultrafiltration (renal)

Continuing Medical Education (CME)

CME Programs on Ultrafiltration (renal)


Ultrafiltration (renal) en Espanol

Ultrafiltration (renal) en Francais


Ultrafiltration (renal) in the Marketplace

Patents on Ultrafiltration (renal)

Experimental / Informatics

List of terms related to Ultrafiltration (renal)

In biological terms, Ultrafiltration occurs at the barrier between the blood and the filtrate in the renal corpuscle or Bowman's capsule in the kidneys. The Bowman's capsule contains a dense capillary network called the glomerulus. Blood flows into these capillaries through a wide afferent arteriole and leaves through a narrower efferent arteriole. The blood pressure inside these capillaries is high because:

  1. The renal artery contains blood at very high pressure which enters the glomerulus via the short afferent arteriole.
  2. The efferent arteriole has a smaller diameter than the afferent arteriole.

The high pressure forces small molecules such as water, glucose, amino acids, sodium chloride and urea through the filter, from the blood in the glomerular capsule across the basement membrane of the Bowman's capsule and into the nephron. This type of high pressure filtration is ultrafiltration. The fluid formed in this way is called glomerular filtrate. Molecules such as plasma proteins and blood cells do not pass through the filter because they are too big.

Glomerular pressure is about 75 millimeters of mercury (10 kPa). It is opposed by osmotic pressure(30 mmHg, 4.0 kPa) and hydrostatic pressure (20 mmHg, 2.7 kPa) of solutes present in capsular space. This difference in pressure is called effective pressure(25 mmHg)(3.3 kPa).

It is also used in hemodialysis to clean whole blood while keeping its composition intact.

Slow Continuous Ultrafiltration

Slow Continuous Ultrafiltration (SCUF) is an artificial method which approximately mimics the ultrafiltration function of the kidneys. SCUF is a continuous renal replacement therapy (CRRT) generally used to remove fluid from fluid overloaded patients suffering acute renal failure. During SCUF blood is removed from the body and is passed through an extracorporeal circuit through a hemofilter and a predetermined percentage of plasma water is removed based upon a prescription. Typically, no more than 2 liters an hour of fluid is removed. The remaining blood is returned to the patient. Unlike hemodialysis, hemofiltration and hemodiafiltration, no dialysate or replacement fluids are used in SCUF. [1]

Template:WikiDoc Sources