P-type ATPase

Jump to navigation Jump to search
1wpg opm.gif
Calcium ATPase, E2-Pi state
OPM superfamily22
OPM protein1wpg

WikiDoc Resources for P-type ATPase


Most recent articles on P-type ATPase

Most cited articles on P-type ATPase

Review articles on P-type ATPase

Articles on P-type ATPase in N Eng J Med, Lancet, BMJ


Powerpoint slides on P-type ATPase

Images of P-type ATPase

Photos of P-type ATPase

Podcasts & MP3s on P-type ATPase

Videos on P-type ATPase

Evidence Based Medicine

Cochrane Collaboration on P-type ATPase

Bandolier on P-type ATPase

TRIP on P-type ATPase

Clinical Trials

Ongoing Trials on P-type ATPase at Clinical Trials.gov

Trial results on P-type ATPase

Clinical Trials on P-type ATPase at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on P-type ATPase

NICE Guidance on P-type ATPase


FDA on P-type ATPase

CDC on P-type ATPase


Books on P-type ATPase


P-type ATPase in the news

Be alerted to news on P-type ATPase

News trends on P-type ATPase


Blogs on P-type ATPase


Definitions of P-type ATPase

Patient Resources / Community

Patient resources on P-type ATPase

Discussion groups on P-type ATPase

Patient Handouts on P-type ATPase

Directions to Hospitals Treating P-type ATPase

Risk calculators and risk factors for P-type ATPase

Healthcare Provider Resources

Symptoms of P-type ATPase

Causes & Risk Factors for P-type ATPase

Diagnostic studies for P-type ATPase

Treatment of P-type ATPase

Continuing Medical Education (CME)

CME Programs on P-type ATPase


P-type ATPase en Espanol

P-type ATPase en Francais


P-type ATPase in the Marketplace

Patents on P-type ATPase

Experimental / Informatics

List of terms related to P-type ATPase

P-type (or E1-E2-type) ATPases constitute a superfamily of cation transport enzymes, present both in prokaryota and eukaryota, whose members mediate membrane flux of all common biologically relevant cations[1]. The ATPases, that form an aspartyl phosphate intermediate in the course of ATP hydrolysis, can be divided into 4 major groups[2]:

  • (1) Ca2+-transporting ATPases;
  • (2) Na+/K+- and gastric H+/K+-transporting ATPases;
  • (3) Plasma membrane H+-transporting ATPases (proton pumps) of plants, fungi and lower eukaryotes; and
  • (4) all bacterial P-type ATPases, except the Mg2+-ATPase of Salmonella typhimurium, which is more similar to the eukaryotic sequences.

Human proteins containing this domain

See also


  1. Maguire ME, Smith DL, Tao T (1993). "Membrane topology of a P-type ATPase. The MgtB magnesium transport protein of Salmonella typhimurium". J. Biol. Chem. 268 (30): 22469–22479. PMID 8226755.<templatestyles src="Module:Citation/CS1/styles.css"></templatestyles>
  2. Fagan MJ, Saier Jr MH (1994). "P-type ATPases of eukaryotes and bacteria: sequence analyses and construction of phylogenetic trees". J. Mol. Evol. 38 (1): 57–99. PMID 8151716.<templatestyles src="Module:Citation/CS1/styles.css"></templatestyles>

Template:WH Template:WS