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E number{{#property:P628}}
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Chemical and physical data
Molar mass522.717 g/mol

O-1057 is a drug which is a cannabinoid derivative. It has analgesic effects and is used in scientific research. Unlike most cannabinoid agonists it is water soluble, which gives it advantages over other drugs in this family. It has moderate affinity for both CB1 and CB2 receptors, with Ki values of 8.36nM at CB1 and 7.95nM at CB2.[1] The letter O stands for Organix Inc., a chemical research company.



  1. Pertwee RG, Gibson TM, Stevenson LA, Ross RA, Banner WK, Saha B, Razdan RK, Martin BR. O-1057, a potent water-soluble cannabinoid receptor agonist with antinociceptive properties. British Journal of Pharmacology. 2000 Apr;129(8):1577-84. PMID 10780961

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