Hemorrhagic diathesis

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Hemorrhagic diathesis
DiseasesDB 1442

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Synonyms and keywords: Bleeding tendency; haemostasis abnormality; hemorrhagic diathesis; bleeding diathesis


Bleeding diathesis is an unusual susceptibility to bleeding (hemorrhage) due to a defect in the system of coagulation. Several types are distinguished, ranging from mild to lethal.


Common Causes

  • Anticoagulation therapy
  • Hepatopathies
  • Hereditary coagulopathies
  • Thrombocyte impairment
  • Vitamin K deficiency

Causes by Organ System

Cardiovascular Anaphylactic shock, Bacterial endocarditis, Cyanotic cardiac vitium, Diffuse intravascular coagulation, Large vascular prostheses, Marfan's syndrome, Myocardial infarction, Vascular hemostatic disorder, Vascular purpura, Vasculitis,
Chemical/Poisoning Bothrop venom, Rattlesnake venom, Viper venom
Dental No underlying causes
Dermatologic Henoch-schonlein purpura, Measles, Nonthrombocytopenic purpura, Osler's disease, Scurvy, Senile-atrophic senilis
Drug Side Effect Anti-aggregation with aspirin, Anticoagulation inhibitors, Cobimetinib, Epoprostenol, Factor viii inhibitors, Propylthiouracil, Ramucirumab, Therapy with cholestyramin, Warfarin
Ear Nose Throat No underlying causes
Endocrine Amyloidosis, Chronic hypercortisolism, Cushing's syndrome, Hermansky-pudlak syndrome,
Environmental No underlying causes
Gastroenterologic Acute pancreatitis, Biliary cirrhosis, Cirrhosis, Faulty intestinal flora, Liver failure, Severe gastrointestinal bleeding, Severe hepatopathy, Splenomegaly with portal hypertension
Genetic Ehlers-danlos syndrome, Osteogenesis imperfecta, Pseudoxanthoma elasticum, Wiskott-aldrich syndrome
Hematologic Ehlers-danlos syndrome, Osteogenesis imperfecta, Pseudoxanthoma elasticum, Wiskott-aldrich syndrome
Iatrogenic Fibrinolysis therapy, Fibrinolytic fission products, Graft vs. host disease, Grey platelet syndrome, Large operations, Large vascular prostheses,
Infectious Disease Bacterial endocarditis, Bacterial meningitis, Cephalosporins, Dengue hemorrhagic fever, Dengue shock syndrome, Diptheria, Influenza, Leptospirosis, Malaria, Measles, Rickettsia, Scarlet fever, Scurvy, Sepsis, Syphilis, Toxoplasmosis, Varicella
Musculoskeletal/Orthopedic Myelodysplasia, Myeloproliferative syndrome
Neurologic Bacterial meningitis, Cranio cerebral trauma, Large aneurysms, Osler's disease
Nutritional/Metabolic Avitaminosis c, Cirrhosis, Dietary deficiencies, Malabsorption, Parenteral nutrition, Vitamin k deficiency
Obstetric/Gynecologic Amniotic fluid embolism, Intrauterine embryo death, Parenteral nutrition, Premature placenta ablation, Septic abortion
Oncologic Carcinomas, Leukemia, Myelodysplasia, Myeloproliferative syndrome
Overdose/Toxicity No underlying causes
Psychiatric No underlying causes
Pulmonary Anaphylactic shock
Renal/Electrolyte Lactic acidosis, Renal failure, Uremia
Rheumatology/Immunology/Allergy Cystic fibrosis, Dysfibrinogenemia
Sexual Syphilis
Trauma Burns, Cranio cerebral trauma, Hypothermia, Intrauterine embryo death
Urologic Uremia
Miscellaneous No underlying causes

Causes In Alphabetical Order. [1] [2]


  1. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:77 ISBN 1591032016
  2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:68 ISBN 140510368X

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