HIV induced pericarditis laboratory studies

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Pericarditis Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ramyar Ghandriz MD[2]

Overview

Laboratory findings depend on the type of disease affecting the heart. Culture and serology are used to diagnose infections causing pericarditis and myocarditis.

Laboratory Findings

  • Cutaneous anergy is common in AIDS due to immunosuppression.[1] Therefore a negative skin test for tuberculosis does not exclude the diagnosis of tuberculous pericarditis. Hence, pericardial biopsy is a more sensitive and preferred diagnostic test over smears and cultures.[2]
  • Other infections that cause pericarditis can be diagnosed by staining, culture and smears.[3]

References

  1. Mukadi, Y; Perriëns, J.H; St Louis, M.E; Brown, C; Ryder, R.W; Perriëns, J.H; Portaels, F; Piot, P; Perriëns, J.H; Willame, J-C; St Louis, M.E; Ryder, R.W; Brown, C; Prignot, J; Pouthier, F; Willame, J-C; Kaboto, M (1993). "Spectrum of immunodeficiency in HIV-1-infected patients with pulmonary tuberculosis in Zaire". The Lancet. 342 (8864): 143–146. doi:10.1016/0140-6736(93)91346-N. ISSN 0140-6736.
  2. Ntsekhe, Mpiko; Mayosi, Bongani M. (2012). "Tuberculous pericarditis with and without HIV". Heart Failure Reviews. 18 (3): 367–373. doi:10.1007/s10741-012-9310-6. ISSN 1382-4147.
  3. Trautner, Barbara W.; Darouiche, Rabih O. (2001). "Tuberculous Pericarditis: Optimal Diagnosis and Management". Clinical Infectious Diseases. 33 (7): 954–961. doi:10.1086/322621. ISSN 1058-4838.


Cardiology