Jump to navigation Jump to search

Template:DiseaseDisorder infobox

WikiDoc Resources for Erythroplakia


Most recent articles on Erythroplakia

Most cited articles on Erythroplakia

Review articles on Erythroplakia

Articles on Erythroplakia in N Eng J Med, Lancet, BMJ


Powerpoint slides on Erythroplakia

Images of Erythroplakia

Photos of Erythroplakia

Podcasts & MP3s on Erythroplakia

Videos on Erythroplakia

Evidence Based Medicine

Cochrane Collaboration on Erythroplakia

Bandolier on Erythroplakia

TRIP on Erythroplakia

Clinical Trials

Ongoing Trials on Erythroplakia at Clinical

Trial results on Erythroplakia

Clinical Trials on Erythroplakia at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Erythroplakia

NICE Guidance on Erythroplakia


FDA on Erythroplakia

CDC on Erythroplakia


Books on Erythroplakia


Erythroplakia in the news

Be alerted to news on Erythroplakia

News trends on Erythroplakia


Blogs on Erythroplakia


Definitions of Erythroplakia

Patient Resources / Community

Patient resources on Erythroplakia

Discussion groups on Erythroplakia

Patient Handouts on Erythroplakia

Directions to Hospitals Treating Erythroplakia

Risk calculators and risk factors for Erythroplakia

Healthcare Provider Resources

Symptoms of Erythroplakia

Causes & Risk Factors for Erythroplakia

Diagnostic studies for Erythroplakia

Treatment of Erythroplakia

Continuing Medical Education (CME)

CME Programs on Erythroplakia


Erythroplakia en Espanol

Erythroplakia en Francais


Erythroplakia in the Marketplace

Patents on Erythroplakia

Experimental / Informatics

List of terms related to Erythroplakia

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Erythroplakia is a flat red patch or lesion in the mouth that cannot be attributed to any other pathology. There are many other conditions that are similar in appearance and must be ruled out before a diagnosis of erythroplakia is made. Sometimes, a diagnosis is delayed for up to two weeks in order to see if the lesion spontaneously regresses on its own or if another cause can be found. Erythroplakia frequently is associated with dysplasia, and is thus a pre-cancerous lesion.

Erythroplakia has an unknown cause but researchers presume it to be similar to the cause of squamous cell carcinoma. It is mostly found in elderly men around the ages of 65 - 74. It is commonly associated with smoking. The most common areas in the mouth where erythroplakia is found are the floor of the mouth, the tongue, and the soft palate. It appears as a red macule or plaque with well-demarcated borders. The texture is characterized as soft and velvety. An adjacent area of leukoplakia may be found along with the erythroplakia.

Microscopically, the tissue exhibits severe epithelial dysplasia, carcinoma-in-situ, or invasive squamous cell carcinoma in 90% of cases. There is an absence of keratin production and a reduced amount of epithelial cells. Since the underlying vascular structures are less hidden by tissue, erythroplakia appears red when viewed in a clinical setting.

Treatment involves biopsy of the lesion to identify extent of dysplasia. Complete excision of the lesion is sometimes advised depending on the histopathology found in the biopsy. Even in these cases, recurrence of the erythroplakia is common and, thus, long-term monitoring is needed.


  • Kahn, Michael A. Basic Oral and Maxillofacial Pathology. Volume 1. 2001.

Template:Oral pathology

Template:WH Template:WS