Eclampsia differential diagnosis
Eclampsia differential diagnosis On the Web
American Roentgen Ray Society Images of Eclampsia differential diagnosis
To go back to the main page, click here
Seizures during pregnancy that are unrelated to Preeclampsia need to be distinguished from Eclampsia. This is essential to recognize the correct cause and provide the targeted treatment necessary in a timely manner.
Differentiating Eclampsia from other Diseases
Eclampsia must be differentiated from other diseases that can cause seizures during pregnancy. The differentiation can be done by obtaining a proper history, physical examination, diagnostic tests, or imaging. Such disorders include:
- Acute exacerbation of systemic lupus erythematous
- Adrenal Insufficiency or Acute Adrenal crisis
- Aneurysm of the brain
- Brain tumor
- Cerebellar Haemorrhage
- Disseminated herpes simplex/ Herpes Simplex Encephalitis (HSE)
- Disseminated sepsis syndromes
- Drug Overdose syndromes
- Drug Withdrawal syndromes
- Acute Fatty liver of pregnancy (AFLP)
- Hemolytic uremic syndrome (HUS)
- Hypertensive encephalopathy
- Medication- or drug-induced seizures
- Posterior reversible encephalopathy syndrome (PRES)
- Primary Hyperaldosteronism
- Seizure disorders and Epilepsy
- Stroke (Hemorrhagic or Ischemic)
- Thrombotic thrombocytopenic purpura
Usually, the presence of the signs of severe preeclampsia that precede and accompany eclampsia facilitates the diagnosis.
|Differential Diagnosis||Similar Features||Differentiating Features|
|Acute exacerbation of SLE||
|Acute adrenal insufficiency||
|Intracranial Haemorrhage/ Ruptured Brain Aneurysm||
|Disseminated herpes simplex/ Herpes Simplex Encephalitis(HSE)||
|Drug overdose/Drug Intoxication||
|Drug Withdral Syndromes||
|Acute Fatty Liver of Pregnancy (AFLP)||
- A. Chrisoulidou, C. Williamson, M. De Swiet, Assessment of adrenocortical function in women taking exogenous glucocorticoids during pregnancy. J. Obstet. Gynaecol. 23(6), 643–644 (2003)
- Drucker D, Shumak S, Angel A. Schmidt's syndrome presenting with intrauterine growth retardation and postpartum addisonian crisis. Am J Obstet Gynecol. 1984 May 15;149(2):229-30. doi: 10.1016/0002-9378(84)90206-0. PMID: 6720805.
- Hala M. Goma (April 10th 2013). Management of Brain Tumor in Pregnancy — An Anesthesia Window, Clinical Management and Evolving Novel Therapeutic Strategies for Patients with Brain Tumors, Terry Lichtor, IntechOpen, DOI: 10.5772/54250. Available from: https://www.intechopen.com/chapters/43971
- Misra UK, Tan CT, Kalita J (2008). "Viral encephalitis and epilepsy". Epilepsia. 49 Suppl 6: 13–8. doi:10.1111/j.1528-1167.2008.01751.x. PMID 18754956.
- Chen HY, Albertson TE, Olson KR (2016). "Treatment of drug-induced seizures". Br J Clin Pharmacol. 81 (3): 412–9. doi:10.1111/bcp.12720. PMC 4767205. PMID 26174744.
- Michael BD, Solomon T (2012). "Seizures and encephalitis: clinical features, management, and potential pathophysiologic mechanisms". Epilepsia. 53 Suppl 4: 63–71. doi:10.1111/j.1528-1167.2012.03615.x. PMID 22946723.
- Ko H, Yoshida EM (2006). "Acute fatty liver of pregnancy". Can J Gastroenterol. 20 (1): 25–30. doi:10.1155/2006/638131. PMC 2538964. PMID 16432556.