ERF (gene)

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External IDsGeneCards: [1]
RefSeq (mRNA)



RefSeq (protein)



Location (UCSC)n/an/a
PubMed searchn/an/a
View/Edit Human

ETS domain-containing transcription factor ERF is a protein that in humans is encoded by the ERF gene.[1][2][3]


  1. Sgouras DN, Athanasiou MA, Beal GJ, Fisher RJ, Blair DG, Mavrothalassitis GJ (October 1995). "ERF: an ETS domain protein with strong transcriptional repressor activity, can suppress ets-associated tumorigenesis and is regulated by phosphorylation during cell cycle and mitogenic stimulation". The EMBO Journal. 14 (19): 4781–93. PMC 394576. PMID 7588608.<templatestyles src="Module:Citation/CS1/styles.css"></templatestyles>
  2. de Castro CM, Rabe SM, Langdon SD, Fleenor DE, Slentz-Kesler K, Ahmed MN, Qumsiyeh MB, Kaufman RE (June 1997). "Genomic structure and chromosomal localization of the novel ETS factor, PE-2 (ERF)". Genomics. 42 (2): 227–35. doi:10.1006/geno.1997.4730. PMID 9192842.<templatestyles src="Module:Citation/CS1/styles.css"></templatestyles>
  3. "Entrez Gene: ERF Ets2 repressor factor".<templatestyles src="Module:Citation/CS1/styles.css"></templatestyles>

Further reading

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  • Liu D, Pavlopoulos E, Modi W, Moschonas N, Mavrothalassitis G (March 1997). "ERF: genomic organization, chromosomal localization and promoter analysis of the human and mouse genes". Oncogene. 14 (12): 1445–51. doi:10.1038/sj.onc.1200965. PMID 9136988.<templatestyles src="Module:Citation/CS1/styles.css"></templatestyles>
  • Le Gallic L, Sgouras D, Beal G, Mavrothalassitis G (June 1999). "Transcriptional repressor ERF is a Ras/mitogen-activated protein kinase target that regulates cellular proliferation". Molecular and Cellular Biology. 19 (6): 4121–33. PMC 104371. PMID 10330152.<templatestyles src="Module:Citation/CS1/styles.css"></templatestyles>
  • Dintilhac A, Bernués J (March 2002). "HMGB1 interacts with many apparently unrelated proteins by recognizing short amino acid sequences". The Journal of Biological Chemistry. 277 (9): 7021–8. doi:10.1074/jbc.M108417200. PMID 11748221.<templatestyles src="Module:Citation/CS1/styles.css"></templatestyles>
  • Dubois T, Howell S, Zemlickova E, Aitken A (April 2002). "Identification of casein kinase Ialpha interacting protein partners". FEBS Letters. 517 (1–3): 167–71. doi:10.1016/S0014-5793(02)02614-5. PMID 12062430.<templatestyles src="Module:Citation/CS1/styles.css"></templatestyles>
  • Bain M, Mendelson M, Sinclair J (January 2003). "Ets-2 Repressor Factor (ERF) mediates repression of the human cytomegalovirus major immediate-early promoter in undifferentiated non-permissive cells". The Journal of General Virology. 84 (Pt 1): 41–9. doi:10.1099/vir.0.18633-0. PMID 12533699.<templatestyles src="Module:Citation/CS1/styles.css"></templatestyles>
  • Xiao X, Athanasiou M, Sidorov IA, Horikawa I, Cremona G, Blair D, Barret JC, Dimitrov DS (December 2003). "Role of Ets/Id proteins for telomerase regulation in human cancer cells". Experimental and Molecular Pathology. 75 (3): 238–47. doi:10.1016/S0014-4800(03)00092-3. PMID 14611815.<templatestyles src="Module:Citation/CS1/styles.css"></templatestyles>
  • Wolvetang EJ, Bradfield OM, Hatzistavrou T, Crack PJ, Busciglio J, Kola I, Hertzog PJ (December 2003). "Overexpression of the chromosome 21 transcription factor Ets2 induces neuronal apoptosis". Neurobiology of Disease. 14 (3): 349–56. doi:10.1016/S0969-9961(03)00107-4. PMID 14678752.<templatestyles src="Module:Citation/CS1/styles.css"></templatestyles>
  • Le Gallic L, Virgilio L, Cohen P, Biteau B, Mavrothalassitis G (February 2004). "ERF nuclear shuttling, a continuous monitor of Erk activity that links it to cell cycle progression". Molecular and Cellular Biology. 24 (3): 1206–18. doi:10.1128/MCB.24.3.1206-1218.2004. PMC 321421. PMID 14729966.<templatestyles src="Module:Citation/CS1/styles.css"></templatestyles>
  • Beausoleil SA, Villén J, Gerber SA, Rush J, Gygi SP (October 2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nature Biotechnology. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243.<templatestyles src="Module:Citation/CS1/styles.css"></templatestyles>
  • Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (November 2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.<templatestyles src="Module:Citation/CS1/styles.css"></templatestyles>
  • Hester KD, Verhelle D, Escoubet-Lozach L, Luna R, Rose DW, Glass CK (July 2007). "Differential repression of c-myc and cdc2 gene expression by ERF and PE-1/METS". Cell Cycle. 6 (13): 1594–604. doi:10.4161/cc.6.13.4336. PMID 17525531.<templatestyles src="Module:Citation/CS1/styles.css"></templatestyles>
  • Verykokakis M, Papadaki C, Vorgia E, Le Gallic L, Mavrothalassitis G (October 2007). "The RAS-dependent ERF control of cell proliferation and differentiation is mediated by c-Myc repression". The Journal of Biological Chemistry. 282 (41): 30285–94. doi:10.1074/jbc.M704428200. PMID 17699159.<templatestyles src="Module:Citation/CS1/styles.css"></templatestyles>

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.