Desoxycorticosterone

Jump to navigation Jump to search
Desoxycorticosterone
File:Desoxycorticosterone.svg
Clinical data
ATC code
Identifiers
CAS Number
PubChem CID
E number{{#property:P628}}
ECHA InfoCard{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
FormulaC21H30O4
Molar mass330.461

WikiDoc Resources for Desoxycorticosterone

Articles

Most recent articles on Desoxycorticosterone

Most cited articles on Desoxycorticosterone

Review articles on Desoxycorticosterone

Articles on Desoxycorticosterone in N Eng J Med, Lancet, BMJ

Media

Powerpoint slides on Desoxycorticosterone

Images of Desoxycorticosterone

Photos of Desoxycorticosterone

Podcasts & MP3s on Desoxycorticosterone

Videos on Desoxycorticosterone

Evidence Based Medicine

Cochrane Collaboration on Desoxycorticosterone

Bandolier on Desoxycorticosterone

TRIP on Desoxycorticosterone

Clinical Trials

Ongoing Trials on Desoxycorticosterone at Clinical Trials.gov

Trial results on Desoxycorticosterone

Clinical Trials on Desoxycorticosterone at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Desoxycorticosterone

NICE Guidance on Desoxycorticosterone

NHS PRODIGY Guidance

FDA on Desoxycorticosterone

CDC on Desoxycorticosterone

Books

Books on Desoxycorticosterone

News

Desoxycorticosterone in the news

Be alerted to news on Desoxycorticosterone

News trends on Desoxycorticosterone

Commentary

Blogs on Desoxycorticosterone

Definitions

Definitions of Desoxycorticosterone

Patient Resources / Community

Patient resources on Desoxycorticosterone

Discussion groups on Desoxycorticosterone

Patient Handouts on Desoxycorticosterone

Directions to Hospitals Treating Desoxycorticosterone

Risk calculators and risk factors for Desoxycorticosterone

Healthcare Provider Resources

Symptoms of Desoxycorticosterone

Causes & Risk Factors for Desoxycorticosterone

Diagnostic studies for Desoxycorticosterone

Treatment of Desoxycorticosterone

Continuing Medical Education (CME)

CME Programs on Desoxycorticosterone

International

Desoxycorticosterone en Espanol

Desoxycorticosterone en Francais

Business

Desoxycorticosterone in the Marketplace

Patents on Desoxycorticosterone

Experimental / Informatics

List of terms related to Desoxycorticosterone

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Desoxycorticosterone (11-deoxycorticosterone) is a mineralocorticoid secreted from Zona reticularis and Zona fasciculata of the adrenal gland. In the cytosol of the mitochondrion, pregnenolone is converted to either androgens or 11-deoxycorticosterone and 11-deoxycortisol by enzymes of the endoplasmic reticulum. Then, 11-deoxycorticosterone, along with 11-deoxycortisol, re-enters the mitochondrion, where the enzymes are located for tissue-specific conversion to mineralocorticoids or glucocorticoids, respectively.

Desoxycorticosterone is commonly found in two forms: the acetate salt (desoxycorticosterone acetate, or DOCA) and the pivalate salt (desoxycorticosterone pivalate). Both forms are given as intramuscular injections as replacement therapy for Addison's disease. This disease is marked by insufficient adrenal function, including low mineralocorticoid levels.

Desoxycorticosterone pivalate is sold for veterinary use by Novartis under the brand name Percoten.

References

http://web.indstate.edu/thcme/mwking/steroid-hormones.html

Template:Corticosteroids Template:Corticosteroids for systemic use Template:Jb1 Template:WH Template:WS