Chronic cholecystitis causes

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vendhan Ramanujam M.B.B.S [2]


Common causes of cholecystitis include cholelithiasis and infections.


Life Threatening Causes

Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated. Acute cholecystitis may become complicated as abscess, gangrene or perforation in patients who are older, with diabetes or who delay seeking treatment. This complicated acute cholecystitis can by itself be life-threatening.[1][2][3][4][5]

Common Causes

Common causes of chronic cholecystitis include:

Less Common Causes

Less common causes of chronic cholecystitis include:

Causes by Organ System

Cardiovascular Cholesterol emboli, gall bladder ischemia, hemobilia, vasculitis
Chemical/Poisoning No underlying causes
Dental No underlying causes
Dermatologic No underlying causes
Drug Side Effect Ceftriaxone, clofibrate, febuxostat, estrogen, octreotide, opiates, oral contraceptives, Pergolide, pramipexole, Rilpivirine, Sorafenib, sunitinib, Teduglutide, Tiagabine, zonisamide
Ear Nose Throat No underlying causes
Endocrine No underlying causes
Environmental No underlying causes
Gastroenterologic Acalculous cholecystitis, ampullary stenosis, calculous cholecystitis, cholelithiasis, cirrhosis, Crohn's disease, gall bladder ischemia, gallbladder carcinoma, gallstones, hemobilia, hepatocellular carcinoma, liver abscess, pancreatic tumor
Genetic Choledochal cyst, sickle cell disease
Hematologic Hemolysis, sickle cell disease
Iatrogenic Percutaneous transhepatic cholangiography
Infectious Disease Ascaris lumbricoides, bacteroides, brucella, campylobacter jejuni, candida, choledochal cyst, coxiella burnetii, echinococcus granulosus, edwardsiella tarda, epstein-barr virus, escherichia coli, flavivirus, hepatitis A, hepatitis B, HIV, infections, isospora, klebsiella, leptospira, liver abscess, microsporidiosis, mycobacterium tuberculosis, opisthorchiasis, plasmodium, salmonella enterica, salmonella infections, salmonella typhi, typhoid fever, vibrio cholerae
Musculoskeletal/Orthopedic No underlying causes
Neurologic No underlying causes
Nutritional/Metabolic No underlying causes
Obstetric/Gynecologic No underlying causes
Oncologic Acute myelogenous leukemia, gallbladder carcinoma, hepatocellular carcinoma, malignancy, pancreatic tumor
Ophthalmologic No underlying causes
Overdose/Toxicity No underlying causes
Psychiatric No underlying causes
Pulmonary No underlying causes
Renal/Electrolyte No underlying causes
Rheumatology/Immunology/Allergy Crohn's disease, Sjogren's syndrome, SLE, vasculitis
Sexual No underlying causes
Trauma Cholesterol emboli
Urologic No underlying causes
Miscellaneous Idiopathic

Causes in Alphabetical Order


  1. Gouma, DJ.; Obertop, H. (1992). "Acute calculous cholecystitis. What is new in diagnosis and therapy?". HPB Surg. 6 (2): 69–78. PMID 1292590.
  2. Khuroo, MS. (1996). "Ascariasis". Gastroenterol Clin North Am. 25 (3): 553–77. PMID 8863040. Unknown parameter |month= ignored (help)
  3. Araujo, PS.; Medeiros, Z.; Melo, FL.; Maciel, MA.; Melo, HR. "Candida famata-induced fulminating cholecystitis". Rev Soc Bras Med Trop. 46 (6): 795–6. doi:10.1590/0037-8682-0162-2013. PMID 24474028.
  4. Cello, JP. (1998). "AIDS-Related biliary tract disease". Gastrointest Endosc Clin N Am. 8 (4): 963. PMID 9730942. Unknown parameter |month= ignored (help)
  5. Yasri, S.; Wiwanitkit, V. "Acute typhic cholecystitis". Afr J Paediatr Surg. 10 (4): 395. doi:10.4103/0189-6725.125464. PMID 24469500.

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