Difference between revisions of "Uridine diphosphate glucose"

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'''Uridine diphosphate glucose''' ('''uracil-diphosphate glucose''', '''UDP-glucose''') is a [[nucleotide]].  
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'''Uridine diphosphate glucose''' ('''uracil-diphosphate glucose''', '''UDP-glucose''') is a [[nucleotide sugar]]. It is involved in [[glycosyltransferase]] reactions in [[metabolism]].
  
 
==Functions==
 
==Functions==
It is used as an activated form of [[glucose]] used in [[cell (biology)|cells]] as a substrate for [[glycosyltransferase]]s.<ref>{{cite journal |author=Rademacher T, Parekh R, Dwek R |title=Glycobiology |journal=Annu Rev Biochem |volume=57 |issue= |pages=785-838 |year=1988 |pmid=3052290}}</ref>  
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It is used in [[nucleotide sugars metabolism]] as an activated form of [[glucose]] as a substrate for enzymes called [[glucosyltransferase]]s.<ref>{{cite journal |author=Rademacher T, Parekh R, Dwek R |title=Glycobiology |journal=Annu Rev Biochem |volume=57 |issue= |pages=785-838 |year=1988 |pmid=3052290}}</ref>  
  
It is a precursor of glycogen and can be converted into [[UDP-galactose]] and [[UDP-glucuronic acid]], which can then be used as substrates by the enzymes that make [[polysaccharide]]s containing [[galactose]] and [[glucuronic acid]].  
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It is a precursor of [[glycogen]] and can be converted into [[UDP-galactose]] and [[UDP-glucuronic acid]], which can then be used as substrates by the enzymes that make [[polysaccharide]]s containing [[galactose]] and [[glucuronic acid]].  
  
 
UDP-glucose can also be used as a precursor of sucrose [[lipopolysaccharide]]s, and [[glycosphingolipid]]s.  
 
UDP-glucose can also be used as a precursor of sucrose [[lipopolysaccharide]]s, and [[glycosphingolipid]]s.  
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== See also ==
 
== See also ==
 
 
* [[Nucleoside]]
 
* [[Nucleoside]]
 
* [[Nucleotide]]
 
* [[Nucleotide]]
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* [[Uridine diphosphate]]
 
* [[Uridine diphosphate]]
  
{{Nucleic acids}}
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{{Nucleotide sugars}}
  
 
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{{biochem-stub}}
  
 
[[Category:Nucleotides]]
 
[[Category:Nucleotides]]
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[[Category:Coenzymes]]
  
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[[ja:ウリジン二リン酸グルコース]]
 
[[pl:Urydynodifosforan]]
 
[[pl:Urydynodifosforan]]
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Revision as of 18:58, 13 December 2007

Template:Chembox E number
Uridine diphosphate glucose
Identifiers
3D model (JSmol)
ECHA InfoCard Lua error in Module:Wikidata at line 879: attempt to index field 'wikibase' (a nil value). Lua error in Module:Wikidata at line 879: attempt to index field 'wikibase' (a nil value).
MeSH Uridine+Diphosphate+Glucose
Properties
C15H24N2O17P2
Molar mass 566.302 g/mol
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)

Infobox disclaimer and references

Uridine diphosphate glucose (uracil-diphosphate glucose, UDP-glucose) is a nucleotide sugar. It is involved in glycosyltransferase reactions in metabolism.

Functions

It is used in nucleotide sugars metabolism as an activated form of glucose as a substrate for enzymes called glucosyltransferases.[1]

It is a precursor of glycogen and can be converted into UDP-galactose and UDP-glucuronic acid, which can then be used as substrates by the enzymes that make polysaccharides containing galactose and glucuronic acid.

UDP-glucose can also be used as a precursor of sucrose lipopolysaccharides, and glycosphingolipids.

Components

UDP-glucose consists of the pyrophosphate group, the pentose sugar ribose, glucose, and the nucleobase uracil.

References

  1. Rademacher T, Parekh R, Dwek R (1988). "Glycobiology". Annu Rev Biochem. 57: 785–838. PMID 3052290.

See also


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