Difference between revisions of "Sandbox: malabsorption"

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(Diarrhea)
(Diarrhea)
 
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==Diarrhea==
 
==Diarrhea==
  
<span style="font-size:85%">'''Abbreviations:'''
+
<span style="font-size:85%">'''Abbreviations:''' '''GI:''' [[Gastrointestinal tract|Gastrointestinal]], '''WBC:''' [[White blood cells]], '''Plt:''' [[Platelet|Platelets]], '''Hgb:''' [[Hemoglobin]], '''IgE:''' [[Immunoglobulin E]], '''IgA:''' [[Immunoglobulin A]], '''ETEC:''' [[Escherichia coli enteritis]], '''EPEC''': [[Escherichia coli|Enteropathogenic Escherichia coli]], '''EIEC''': [[Escherichia coli enteritis|Enteroinvasive Escherichia coli]], '''EHEC''': [[Escherichia coli|Enterohemorrhagic Escherichia coli]], '''EAEC''': [[Escherichia coli enteritis|Enteroaggregative Escherichia coli]], '''ESR''': [[Erythrocyte sedimentation rate]], '''CRP''': [[C-reactive protein]],</span>  
'''GI:''' [[Gastrointestinal tract|Gastrointestinal]]; '''WBC:''' [[White blood cells]]; '''Plt:''' [[Platelet|Platelets]], '''Hgb:''' [[Hemoglobin]], '''IgE:''' [[Immunoglobulin E]], '''IgA:''' [[Immunoglobulin A]]  
 
</span>
 
  
 
{| class="wikitable" style="border: 0px; font-size: 100%; margin: 3px;" align="center"
 
{| class="wikitable" style="border: 0px; font-size: 100%; margin: 3px;" align="center"
! rowspan="5" style="background:#4479BA; color: #FFFFFF;" align="center" |Cause
+
! colspan="2" rowspan="5" style="background:#4479BA; color: #FFFFFF;" align="center" |Categories
| colspan="10" style="background:#4479BA; color: #FFFFFF;" align="center" |'''Clinical manifestation'''
+
! colspan="2" rowspan="5" style="background:#4479BA; color: #FFFFFF;" align="center" |Cause
 +
| colspan="9" style="background:#4479BA; color: #FFFFFF;" align="center" |'''Clinical manifestation'''
 
! colspan="9" rowspan="3" style="background:#4479BA; color: #FFFFFF;" align="center" |'''Lab findings'''
 
! colspan="9" rowspan="3" style="background:#4479BA; color: #FFFFFF;" align="center" |'''Lab findings'''
 
! rowspan="5" style="background:#4479BA; color: #FFFFFF;" align="center" |Extra intestinal findings
 
! rowspan="5" style="background:#4479BA; color: #FFFFFF;" align="center" |Extra intestinal findings
Line 13: Line 12:
 
! rowspan="5" style="background:#4479BA; color: #FFFFFF;" align="center" |Gold standard diagnosis
 
! rowspan="5" style="background:#4479BA; color: #FFFFFF;" align="center" |Gold standard diagnosis
 
|-
 
|-
! colspan="9" style="background:#4479BA; color: #FFFFFF;" align="center" |Symptoms
+
! colspan="8" style="background:#4479BA; color: #FFFFFF;" align="center" |Symptoms
 
! rowspan="4" style="background:#4479BA; color: #FFFFFF;" align="center" |GI signs
 
! rowspan="4" style="background:#4479BA; color: #FFFFFF;" align="center" |GI signs
 
|-
 
|-
Line 20: Line 19:
 
! rowspan="3" style="background:#4479BA; color: #FFFFFF;" align="center" |Fever
 
! rowspan="3" style="background:#4479BA; color: #FFFFFF;" align="center" |Fever
 
! rowspan="3" style="background:#4479BA; color: #FFFFFF;" align="center" |Abdominal pain
 
! rowspan="3" style="background:#4479BA; color: #FFFFFF;" align="center" |Abdominal pain
! rowspan="3" |Vomiting
 
 
! rowspan="3" style="background:#4479BA; color: #FFFFFF;" align="center" |Weight loss
 
! rowspan="3" style="background:#4479BA; color: #FFFFFF;" align="center" |Weight loss
 
!
 
!
Line 42: Line 40:
 
! style="background:#4479BA; color: #FFFFFF;" align="center" |Plt
 
! style="background:#4479BA; color: #FFFFFF;" align="center" |Plt
 
|-
 
|-
! style="background:#DCDCDC;" align="center" |[[Whipple's disease]]
+
! colspan="2" rowspan="12" style="background:#4479BA; color: #FFFFFF;" align="center" |Gastrointestinal
 +
! colspan="2" style="background:#DCDCDC;" align="center" |[[Crohns disease]]
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | ±
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | ±
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
|
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
* [[Hepatosplenomegaly]]
+
* [[Abdominal tenderness]]
* [[Ascites]]
+
* [[Oral ulcer|Mouth ulcer]]
 +
* [[Tachycardia]]
 +
* [[Hypotension]]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |-
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |↑
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |↓
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |↑
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
* [[Anti saccharomyces cerevisiae antibodies]] (ASCA)
 +
* [[Vitamin B12]] deficiency
 +
* Elevated [[erythrocyte sedimentation rate|ESR]]
 +
* Elevated [[C-reactive protein|CRP]]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
* [[Uveitis]]
 +
* [[Arthritis]]
 +
* [[Erythema nodosum]]
 +
* [[Pyoderma gangrenosum]]
 +
* [[Amyloidosis]]
 +
* Venous and arterial [[thromboembolism]]
 +
* [[Kidney stone|Renal stones]]
 +
* [[Bronchiectasis]]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
* Abnormal immune response to self [[antigens]]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
* [[Colonoscopy]] with [[biopsy]]
 +
|-
 +
! colspan="2" style="background:#DCDCDC;" align="center" |[[Ulcerative colitis]]
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
* Normal in mild cases
 +
 +
* [[Abdominal tenderness]]
 +
* [[Tachycardia]]
 +
* [[Hypotension]]
 +
* [[Pallor]]
 +
* [[Blood]] on [[rectal examination]]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |-
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |↑
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |↑
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
* [[Fecal fat]]
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |↓
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |↓
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |↑
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |↓/
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
*[[Hypoalbuminemia]]
+
* [[Anti-neutrophil cytoplasmic antibody]] ([[P-ANCA]])
 +
* [[Hypoalbuminemia]]
 +
* [[Hypokalemia]]
 +
* [[Hypomagnesemia]]
 +
* Elevated [[Erythrocyte sedimentation rate|ESR]]
 +
* Elevated [[C-reactive protein|CRP]]
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
* [[Ocular motility disorders|Abnormal extraocular movement]]
+
* [[Skin rash]]
* [[Lymphadenopathy]]
+
* [[Iritis]]
* [[Hyperpigmentation]]
 
 
* [[Uveitis]]
 
* [[Uveitis]]
* [[Endocarditis]]
+
* Seronegative [[arthritis]]
* [[Encephalitis]]
+
* [[Clubbing]] of the fingers
* [[Dementia]]
+
* [[Erythema nodosum]]
* [[Pleural effusion]]
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
* [[Tropheryma whipplei]]
+
* Abnormal immune response to self [[antigens]]
* [[HLA-B27]]
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
* [[Small intestine]] [[biopsy]] for [[Tropheryma whipplei]] testing
+
* [[Colonoscopy]] with [[biopsy]]
* [[PCR]] testing
 
 
|-
 
|-
! style="background:#DCDCDC;" align="center" |[[Celiac disease]]
+
! colspan="2" style="background:#DCDCDC;" align="center" |[[Celiac disease]]
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
Line 90: Line 134:
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
|
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
Line 99: Line 142:
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
+
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
*
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | ↓
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | ↓
Line 121: Line 165:
 
* [[IgA]] tissue transglutaminase antibody
 
* [[IgA]] tissue transglutaminase antibody
 
|-
 
|-
! style="background:#DCDCDC;" align="center" |[[Tropical sprue]]
+
! colspan="2" style="background:#DCDCDC;" align="center" |[[Cystic fibrosis]]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |±
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |↓
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
* Positive [[DNA]] analysis for [[CFTR]]
 +
* Nasal transepithelial potential difference
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
* [[Diabetes]]
 +
* Recurrent upper and lower [[respiratory tract infections]]
 +
* [[Infertility]]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
* Mutations in the [[cystic fibrosis transmembrane conductance regulator]] ([[CFTR]]) protein
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
* Elevated [[Sweat chloride test|sweat chloride]] ≥60 mmol/L
 +
|-
 +
! colspan="2" style="background:#DCDCDC;" align="center" |[[Chronic pancreatitis]]
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
|
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
* [[Pallor]]
 
* Angular [[stomatitis]]
 
* [[Oral ulcer|Mouth ulcers]]
 
* [[Edema]]
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
* [[Tenderness (medicine)|Abdominal tenderness]]
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |↑
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | ↓
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |  
+
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |
* [[Vitamin B12 deficiency|Low vitamin B12]]
+
*
* [[Folate deficiency|Low folic acid]]
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
* [[Hypokalemia]] 
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |  
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |  
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
* Unknown
+
* Slightly elevated amylase and lipase
* [[Bacteria]] including ''[[Escherichia coli]]'', ''[[Klebsiella pneumoniae]]'', ''[[Enterobacter cloacae]]''
+
* Abnormal pancreatic function test
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |  
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
* Diagnosis of exclusion
+
* [[Malabsorption]]
 +
* [[Diabetes mellitus]]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
* Repeated acute pancreatitis
 +
* Alcohol abuse
 +
* Genetic
 +
* Autoimmune
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
* [[Secretin]] stimulation test
 +
* [[Endoscopic retrograde cholangiopancreatography|ERCP]]
 +
|-
 +
! colspan="2" |[[Bile acid malabsorption]]
 +
!
 +
!
 +
!
 +
!
 +
!
 +
!
 +
!
 +
!
 +
!
 +
!
 +
!
 +
!
 +
!
 +
!
 +
!
 +
!
 +
!
 +
!
 +
!
 +
!
 +
!
 
|-
 
|-
! style="background:#DCDCDC;" align="center" |[[Crohns disease]]
+
! colspan="2" style="background:#DCDCDC;" align="center" |[[Microscopic colitis]]
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
|
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
* [[Abdominal tenderness]]
 
* [[Abdominal tenderness]]
* [[Tachycardia]]
 
* [[Hypotension]]
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
+
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |↓
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |↓
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
* [[Iron deficiency]]
+
* Elevated [[autoantibodies]] include:
* [[Vitamin B12]] deficiency
+
**[[RF]]
* Elevated [[erythrocyte sedimentation rate|ESR]]  
+
**[[ANA]]
* Elevated [[C-reactive protein|CRP]]
+
**[[Anti-mitochondrial antibody|AMA]]
 +
**[[ANCA]]
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
* Blood seen on [[rectal exam]]
+
* Fecal urgency
 +
* Fecal [[incontinence]]
 +
* [[Arthralgia]]
 +
* [[Arthritis]]
 +
* [[Uveitis]]
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
* Abnormal immune response to self [[antigens]]
+
* [[Mucosal]] [[immune responses]] to luminal factors in a genetically predisposed individual
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
* [[Colonoscopy]] with [[biopsy]]
+
* [[Colonoscopy]] with [[mucosal]] [[biopsy]] with [[mononuclear]] infiltrates:
 +
** [[Collagenous colitis]] is characterized by a colonic subepithelial [[collagen]] band >10 micrometers in diameter
 +
** [[Lymphocytic]] [[colitis]] is characterized by ≥20 intraepithelial [[lymphocytes]] (IEL) per 100 surface epithelial cells
 
|-
 
|-
! style="background:#DCDCDC;" align="center" |[[Ulcerative colitis]]
+
! colspan="2" style="background:#DCDCDC;" align="center" |[[Infective colitis]]
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
|
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
* [[Abdominal tenderness]]
 
* [[Tachycardia]]
 
* [[Hypotension]]
 
* [[Aphthous ulcers]]
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="Left" |
 +
*
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |↑
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |↓
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |↑
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
* Hypoalbuminemia
+
*
* Hypokalemia
 
* Hypomagnesemia
 
* Iron deficiency
 
* Elevated ESR
 
* Elevated CRP
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
* [[Skin rash]]
+
*
* [[Iritis]]
 
* [[Uveitis]]
 
* Seronegative [[arthritis]]
 
* [[Clubbing]] of the fingers
 
* [[Erythema nodosum]]
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
* Abnormal immune response to self [[antigens]]
+
*
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
* [[Colonoscopy]] with [[biopsy]]
+
*
 
|-
 
|-
! style="background:#DCDCDC;" align="center" |[[Cystic fibrosis]]
+
! colspan="2" style="background:#DCDCDC;" align="center" |[[Ischemic colitis]]
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="Left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |±
+
*
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
|
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
|-
 +
! colspan="2" style="background:#DCDCDC;" align="center" |[[Mesenteric ischemia]]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="Left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |↓
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
* Positive [[DNA]] analysis for [[CFTR]]
+
*
* Evaluated [[nasal]] transepithelial potential difference (NPD)
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
* [[Diabetes]]
+
*
* Recurrent upper and lower [[respiratory tract infections]]
 
* [[Infertility]]
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
* Mutations in the [[cystic fibrosis transmembrane conductance regulator]] ([[CFTR]]) protein
+
*
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
* Elevated [[Sweat chloride test|sweat chloride]] ≥60 mmol/L
+
*
 
|-
 
|-
! style="background:#DCDCDC;" align="center" |[[VIPoma]]
+
! colspan="2" style="background:#DCDCDC;" align="center" |[[Lactose intolerance]]
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
+
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |  
|
+
* [[Abdominal tenderness ]]
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
+
* [[Hypotension]]
| style="padding: 5px 5px; background: #F5F5F5;" align="Left" |  
+
* [[Tachycardia]]
* [[Tachycardia]]  
+
* [[Nausea and vomiting]]
* [[Abdominal distention]]
 
* Abdominal [[RUQ]] [[tenderness]]
 
* [[Nausea]]
 
* [[Vomiting]]
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
+
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
*
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
*Elevated [[VIP]] level
 
*[[Hypokalemia]]
 
*[[Hypochlorhydria]] or [[achlorhydria]]
 
*Low osmotic gap (<50 mOsm/kg)
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |  
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |  
* [[Rash]]  
+
* [[Hydrogen breath test]]
* [[Facial flushing]]
+
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
* [[Dehydration]]  
+
* [[Bloating]]
* [[Lethargy]]
+
* [[Flatulence]]
* [[Muscle weakness]]
+
* Symptoms begin mainly after ingestion of [[lactose]]
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |  
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |  
* Primary secretory tumor
+
* Reduction of lactase enzyme activity or inability to produce persistent [[lactase]]
 +
* Congenital [[lactase deficiency]]
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |  
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |  
* Elevated [[VIP]] levels
+
* [[Lactase]] activity assay
* Followed by imaging
 
 
|-
 
|-
! style="background:#DCDCDC;" align="center" |[[Zollinger-Ellison syndrome]]
+
! colspan="2" style="background:#DCDCDC;" align="center" |[[Irritable bowel syndrome]]
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |±
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |±
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |±
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
+
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |  
|
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="Left" |
 
 
* [[Abdominal tenderness]]
 
* [[Abdominal tenderness]]
 +
* [[Flatulence]]
 +
* Hard stool in the rectal vault
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |↓
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |↓
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
*
 +
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
*
 +
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
*
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |  
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |  
* Positive [[secretin]] stimulation test
+
* Diagnosis of exclusion
* Elevated serum [[chromogranin A]]
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
* [[Heartburn]]
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
* [[Gastrin]] producing [[tumor]] mainly in [[duodenum]]
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
* Elevated basal or stimulated serum [[gastrin]]> 120 pg/mL
 
 
|-
 
|-
! style="background:#DCDCDC;" align="center" |[[Eosinophilic gastroenteritis]] 
+
! rowspan="33" style="background:#4479BA; color: #FFFFFF;" align="center" |Infection
 +
! rowspan="19" style="background:#4479BA; color: #FFFFFF;" align="center" |Bacterial
 +
! colspan="2" style="background:#DCDCDC;" align="center" |[[Whipple's disease]]
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | ±
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
* [[Hepatosplenomegaly]]
 +
* [[Ascites]]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
* [[Fecal fat]]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |↓
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |↓
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |↓/↑
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*[[Hypoalbuminemia]]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
* [[Ocular motility disorders|Abnormal extraocular movement]]
 +
* [[Lymphadenopathy]]
 +
* [[Hyperpigmentation]]
 +
* [[Uveitis]]
 +
* [[Endocarditis]]
 +
* [[Encephalitis]]
 +
* [[Dementia]]
 +
* [[Pleural effusion]]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
* [[Tropheryma whipplei]]
 +
* [[HLA-B27]]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
* [[Small intestine]] [[biopsy]] for [[Tropheryma whipplei]] testing
 +
* [[PCR]] testing
 +
|-
 +
! colspan="2" style="background:#DCDCDC;" align="center" |[[Tropical sprue]]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
|
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |  
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |  
* [[Abdominal distention]]
+
* [[Pallor]]
 +
* Angular [[stomatitis]]
 +
* [[Oral ulcer|Mouth ulcers]]
 +
* [[Edema]]
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | ↑
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | ↓
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |  
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |  
* Elevated [[serum]] [[IgE]] levels
+
* [[Vitamin B12 deficiency|Low vitamin B12]]  
* [[Eosinophilia]]
+
* [[Folate deficiency|Low folic acid]]
* Elevated [[ESR]]
+
* [[Hypokalemia]] 
* [[Hypoalbuminemia]]
+
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
*
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |  
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |  
* Other [[Allergic disorders|allergic disorders]]
+
* Unknown
* Associated with an identifiable [[dietary]] [[antigen]]
+
* [[Bacteria]] including ''[[Escherichia coli]]'', ''[[Klebsiella pneumoniae]]'', ''[[Enterobacter cloacae]]''
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |  
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |  
* [[Autoimmunity|Autoimmune]] [[Allergy|allergic]] response to food [[antigens]]
+
* Diagnosis of exclusion
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
* [[Eosinophilic]] infiltration of the [[gastrointestinal tract]] on [[biopsy]]
 
 
|-
 
|-
! style="background:#DCDCDC;" align="center" |[[Primary bile acid malabsorption]]
+
! colspan="2" style="background:#DCDCDC;" align="center" |[[Small bowel bacterial overgrowth syndrome|Small bowel bacterial overgrowth]]
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
Line 374: Line 531:
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
|
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
* [[Muscle atrophy]]
 +
 
 +
* [[Abdominal distension|Abdominal distention]]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |↓
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
* [[Hypoalbuminemia]]
 +
* Abnormal [[Hydrogen Breath Test|hydrogen breath test]]
 +
* [[Lactic acidosis]]
 +
* Abnormal [[fecal fat]] test
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
* [[Malabsorption]]
 +
* [[Avitaminosis|Vitamins deficiencies]]
 +
* [[Rosacea]] 
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
* Excess bacteria in the small intestine
 +
* Alterations in intestinal anatomy or GI motility, 
 +
* Lack of gastric acid secretion
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
* Diagnosis of exclusion
 +
|-
 +
! colspan="2" style="background:#DCDCDC;" align="center" |[[Foodborne illness|Food poisoning]]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
+
| style="padding: 5px 5px; background: #F5F5F5;" align="Left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |↓
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |  
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
* Low  [[Vitamin A|vitamins A]], [[Vitamin D|D]], E, and K
+
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
+
*
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
* [[Genetic defects]] in ''SLC10A2'' (solute carrier family 10 member 2 gene)
+
*
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
* Elevated total and specific [[bile acids]] in stool
+
*
* Positive [[SeHCAT]]
 
 
|-
 
|-
! style="background:#DCDCDC;" align="center" |[[Abetalipoproteinemia]]
+
! colspan="2" style="background:#DCDCDC;" align="center" |[[Pseudomembranous enterocolitis|Pseudomembranous colitis]]
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +/-
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
|
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +/-
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
* Abdominal tenderness
 +
* Presence of pseudomembranes of endoscopy
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
* [[Abdominal distension]]
+
* Enzyme immunoassay (EIA) for ''C difficile'' toxin A and B
* [[Visual field defect]]
+
* Polymerase chain reaction (PCR) assay or ''C difficile'' antigen (glutamate dehydrogenase [GDH]) EIA
* [[Dysarthria]]
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |↑
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |↓
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |↓
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
* Leukocytosis
 +
* Elevated serum creatinine
 +
* Hypoalbuminemia
 +
* Anasarca
 +
* Elevated serum lactate
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
* Recent antibiotics use
 +
* Recent surgery
 +
* Colon cancer
 +
* Diverticulitis
 +
* Appendicitis
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
* Stool exam
 +
* CT
 +
|-
 +
! colspan="2" style="background:#DCDCDC;" align="center" |[[Shigella]]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="Left" |
 +
*
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
|-
 +
! colspan="2" style="background:#DCDCDC;" align="center" |[[Salmonella]]
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="Left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
* Low [[triglyceride]]
+
*
* Low total [[cholesterol]] levels 
 
* [[Acanthocytes]]
 
* Low [[vitamin E]] levels
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
* Visual impairment
+
*
* [[Ataxia]]
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
* [[Autosomal recessive]] disorder caused by mutations encoding the [[microsomal]] [[triglyceride]] transfer protein (MTP)
+
*
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
* Clinical findings and low [[triglyceride]] and [[cholesterol]] level
+
*
 
|-
 
|-
! style="background:#DCDCDC;" align="center" |[[Microscopic colitis]]
+
! colspan="2" style="background:#DCDCDC;" align="center" |[[Campylobacter jejuni]]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="Left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
|-
 +
! rowspan="5" style="background:#DCDCDC;" align="center" |[[Escherichia coli|E-coli]]
 +
| style="background:#DCDCDC;" align="center" |[[ETEC|'''ETEC''']]
 +
([[Traveler's diarrhea]])
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
+
| style="padding: 5px 5px; background: #F5F5F5;" align="Left" |
|
+
*
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*Enterotoxins:
 +
**Heat-labile enterotoxin (LT) 
 +
**Heat-stable enterotoxin (ST)
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*Enterotoxins:
 +
**Heat-labile enterotoxin (LT)   Heat-stable enterotoxin (ST)
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
* [[Abdominal tenderness]]
+
*
 +
|-
 +
| style="background:#DCDCDC;" align="center" |[[EPEC|'''EPEC''']]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
+
| style="padding: 5px 5px; background: #F5F5F5;" align="Left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |↓
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
* Elevated [[autoantibodies]] include:
+
*
**[[RF]]
 
**[[ANA]]
 
**[[Anti-mitochondrial antibody|AMA]]
 
**[[ANCA]]
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
* Fecal urgency
+
*
* Fecal [[incontinence]]
 
* [[Arthralgia]]
 
* [[Arthritis]]
 
* [[Uveitis]]
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
* [[Mucosal]] [[immune responses]] to luminal factors in a genetically predisposed individual
+
*
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
* [[Colonoscopy]] with [[mucosal]] [[biopsy]] with [[mononuclear]] infiltrates:
+
*
** [[Collagenous colitis]] is characterized by a colonic subepithelial [[collagen]] band >10 micrometers in diameter
 
** [[Lymphocytic]] [[colitis]] is characterized by ≥20 intraepithelial [[lymphocytes]] (IEL) per 100 surface epithelial cells
 
 
|-
 
|-
! style="background:#DCDCDC;" align="center" |[[Hyperthyroidism]]
+
| style="background:#DCDCDC;" align="center" |[[EIEC|'''EIEC''']]
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="Left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |±
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
+
*
|
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
* Lump in the neck
+
*
* [[Proptosis]]
+
|-
* [[Tremor]]
+
| style="background:#DCDCDC;" align="center" |[[EHEC|'''EHEC''']]
* Increased [[Deep tendon reflex|DTR]]
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="Left" |
 +
*
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
* Elevated [[T4]]
+
*
* Elevated [[T3]]
 
* Decreased [[TSH]]
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
* Lid lag
+
*
* [[Sweating]]
 
* [[Hyperpigmentation]]
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
* [[Graves' disease]]
+
*
* [[Hashimoto's thyroiditis]]
 
* [[Toxic adenoma]]
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
* [[TSH]]
+
*
 
|-
 
|-
! style="background:#DCDCDC;" align="center" |[[Lactose intolerance]]
+
| style="background:#DCDCDC;" align="center" |[[EAEC|'''EAEC''']]
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="Left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
|
+
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
|-
 +
! colspan="2" style="background:#DCDCDC;" align="center" |[[Yersinia enterocolitica]]
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
* [[Abdominal tenderness ]]
 
* [[Hypotension]]
 
* [[Tachycardia]]
 
* [[Nausea and vomiting]]
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="Left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |  
+
*
* [[Hydrogen breath test]]
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |  
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
* [[Bloating]]
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
* [[Flatulence]]
+
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
* Symptoms begin mainly after ingestion of [[lactose]]
+
*
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |  
+
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
* Reduction of lactase enzyme activity or inability to produce persistent [[lactase]]
+
*
* Congenital [[lactase deficiency]]
+
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |  
+
*
* [[Lactase]] activity assay
+
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 
|-
 
|-
! style="background:#DCDCDC;" align="center" |[[Irritable bowel syndrome]]
+
! colspan="2" style="background:#DCDCDC;" align="center" |[[Vibrio cholerae|Vibrio cholera]]
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |±
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="Left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |±
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |±
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
|
+
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
|-
 +
! colspan="2" style="background:#DCDCDC;" align="center" |[[Aeromonas]]
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
* [[Abdominal tenderness]]
 
* [[Flatulence]]
 
* Hard stool in the rectal vault
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="Left" |
 +
*
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
|-
 +
! colspan="2" style="background:#DCDCDC;" align="center" |[[Plesiomonas shigelloides|Plesiomonas]]
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="Left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |  
+
*
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |  
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |  
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
* Diagnosis of exclusion
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 
|-
 
|-
! style="background:#DCDCDC;" align="center" |[[Chronic pancreatitis]]
+
! colspan="2" style="background:#DCDCDC;" align="center" |[[Mycobacterium avium complex]]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +/-
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +/-
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |↓
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*Immune system analysis may show defects
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
|-
 +
! colspan="2" style="background:#DCDCDC;" align="center" |Other infections
 +
* aaaa
 +
* bbbb
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +/-
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
|
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*Stool culture may be positive for responsible organism
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |↑
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
|-
 +
! rowspan="8" style="background:#4479BA; color: #FFFFFF;" align="center" |Virus
 +
! colspan="2" style="background:#DCDCDC;" align="center" |[[Rotavirus]]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
* [[Tenderness (medicine)|Abdominal tenderness]]
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
+
| style="padding: 5px 5px; background: #F5F5F5;" align="Left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
|-
 +
! colspan="2" style="background:#DCDCDC;" align="center" |[[Echovirus]]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="Left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
|-
 +
! colspan="2" style="background:#DCDCDC;" align="center" |[[Adenoviridae|Adenovirus]]
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="Left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
* Slightly elevated amylase and lipase
+
*
* Abnormal pancreatic function test
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
* [[Malabsorption]]
 
* [[Diabetes mellitus]]
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
* Repeated acute pancreatitis
 
* Alcohol abuse
 
* Genetic
 
* Autoimmune
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
* [[Secretin]] stimulation test
+
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
* [[Endoscopic retrograde cholangiopancreatography|ERCP]]
+
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 
|-
 
|-
! style="background:#DCDCDC;" align="center" |[[Cirrhosis]]
+
! colspan="2" style="background:#DCDCDC;" align="center" |[[Norovirus]]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="Left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
|-
 +
! colspan="2" style="background:#DCDCDC;" align="center" |[[CMV colitis]]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +/-
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
|
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +/-
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |↓
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*CD 4 level decreased as it is maily associated with HIV
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
|-
 +
! colspan="2" style="background:#DCDCDC;" align="center" |[[Human Immunodeficiency Virus (HIV)|HIV]]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
* Jaundice
 
* Hepatosplenomegaly
 
* Abdominal distention
 
* Shifting dullness
 
* Asterixis
 
* Skin telangiectasias 
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |↑
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |↓
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |↓
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |↓
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
* Abnormal liver function tests
 
* Prolonged PT/PTT
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
* Coagulopathy
+
| style="padding: 5px 5px; background: #F5F5F5;" align="Left" |
* Portal hypertension
+
*
* Hepatic encephalopathy
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
* [[Alcoholic liver disease]]
 
* Viral hepatitis
 
* [[Non-alcoholic fatty liver disease|Non-alcoholic steatohepatitis]]
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
* Liver biopsy
+
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 
|-
 
|-
! style="background:#DCDCDC;" align="center" |[[Short bowel syndrome]]
+
! rowspan="2" style="background:#DCDCDC;" align="center" |[[Hepatitis]]
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
+
! style="background:#DCDCDC;" align="center" |[[Hepatitis A]]
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="Left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
|
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
* [[Abdominal distension|Abdominal distention]]
+
*
* [[Tenderness (medicine)|Abdominal tenderness]]
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
* Peripheral edema
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
* [[Muscle atrophy]]
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
|-
 +
! style="background:#DCDCDC;" align="center" |[[Hepatitis E]]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
+
| style="padding: 5px 5px; background: #F5F5F5;" align="Left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
*
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
* [[Hypoalbuminemia]]
 
* High level of [[Acute phase protein|acute phase reactant]]
 
* Abnormal liver function tests
 
* Low  vitamin A, B12, C,[[Vitamin D|D]], E, and K level
 
* High [[fecal fat]]
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
* Prior intestinal surgery
 
 
* [[Crohn's disease]]
 
* [[Cancer|Malignancy]]
 
* [[Radiation enteropathy|Radiation enteritis]]
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
* Surgical intestinal resection
+
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |  
+
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 
|-
 
|-
! style="background:#DCDCDC;" align="center" |[[Small bowel bacterial overgrowth syndrome|Small bowel bacterial overgrowth]]
+
! rowspan="6" style="background:#4479BA; color: #FFFFFF;" align="center" |Parasite
 +
! colspan="2" style="background:#DCDCDC;" align="center" |[[Entamoeba histolytica]]
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="Left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
|-
 +
! colspan="2" style="background:#DCDCDC;" align="center" |[[Giardia lamblia|Giardia]]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="Left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
|-
 +
! colspan="2" style="background:#DCDCDC;" align="center" |[[Cryptosporidium]]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="Left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
|
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
* [[Muscle atrophy]]
+
*
 
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
* [[Abdominal distension|Abdominal distention]]
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
|-
 +
! colspan="2" style="background:#DCDCDC;" align="center" |[[Microsporidia]]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="Left" |
 +
*
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |↓
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
* [[Hypoalbuminemia]]
+
*
* Abnormal [[Hydrogen Breath Test|hydrogen breath test]]
 
* [[Lactic acidosis]]
 
* Abnormal [[fecal fat]] test
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
* [[Malabsorption]]
 
* [[Avitaminosis|Vitamins deficiencies]]
 
* [[Rosacea]] 
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
* Excess bacteria in the small intestine
 
* Alterations in intestinal anatomy or GI motility, 
 
* Lack of gastric acid secretion
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
* Diagnosis of exclusion
+
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 
|-
 
|-
! style="background:#DCDCDC;" align="center" | '''[[X-linked agammaglobulinemia]]'''
+
! colspan="2" style="background:#DCDCDC;" align="center" |[[Isospora]]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |↑
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
|-
 +
! colspan="2" style="background:#DCDCDC;" align="center" |Other Parasitic diarrhea
 +
* aaaa
 +
* bbbb
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
|
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +/-
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |↑
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
|-
 +
! colspan="2" rowspan="6" style="background:#4479BA; color: #FFFFFF;" align="center" |Tumors
 +
! colspan="2" style="background:#DCDCDC;" align="center" |[[Carcinoid syndrome|Carcinoid tumor]]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
* Signs of dehydration
 
* Signs of infections
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="Left" |
 +
*
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |↓
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |↓
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |↓
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
* Hypogammaglobulinemia
+
*
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
* Recurrent respiratory tract infections
 
* Gastroenteritis
 
* Bacterial infections
 
* Malabsorption
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
* Inherited Gene defect 
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
* Low circulating immunoglobulin levels (IgG, IgA, IgM, IgE) on blood tests
+
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 
|-
 
|-
! style="background:#DCDCDC;" align="center" |Intestinal [[lymphangiectasia]]
+
! colspan="2" style="background:#DCDCDC;" align="center" |[[VIPoma]]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="Left" |
 +
* [[Tachycardia]]
 +
* [[Abdominal distention]]
 +
* Abdominal [[RUQ]] [[tenderness]]
 +
* [[Nausea]]
 +
* [[Vomiting]]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |↓
 +
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*Elevated [[VIP]] level
 +
*[[Hypokalemia]]
 +
*[[Hypochlorhydria]] or [[achlorhydria]]
 +
*Low osmotic gap (<50 mOsm/kg)
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
* [[Rash]]
 +
* [[Facial flushing]]
 +
* [[Dehydration]]
 +
* [[Lethargy]]
 +
* [[Muscle weakness]]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
* Primary secretory tumor
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
* Elevated [[VIP]] levels
 +
* Followed by imaging
 +
|-
 +
! colspan="2" style="background:#DCDCDC;" align="center" |[[Zollinger-Ellison syndrome]]
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
|
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
* Peripheral edema
+
| style="padding: 5px 5px; background: #F5F5F5;" align="Left" |
* Macular edema 
+
* [[Abdominal tenderness]]
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |↓
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |↓
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
* Positive [[secretin]] stimulation test
 +
* Elevated serum [[chromogranin A]]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
* [[Heartburn]]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
* [[Gastrin]] producing [[tumor]] mainly in [[duodenum]]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
* Elevated basal or stimulated serum [[gastrin]]> 120 pg/mL
 +
|-
 +
! colspan="2" style="background:#DCDCDC;" align="center" |[[Neuroendocrine tumors|Somatostatinoma]]
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
* Hypoproteinemia
 
* Hypogammaglobulinemia
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
* Protein-losing enteropathy
 
* Malabsorption
 
* Anergy
 
* Homograft rejection
 
* Pachydermoperiostosis 
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
* Dilatation of intestinal lymphatics
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |Intestinal biopsy
 
|-
 
! style="background:#DCDCDC;" align="center" |[[Amyloidosis]]
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
|
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="Left" |
 +
*
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |↓
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
*
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |  
+
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |  
+
*
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
+
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |  
+
*
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
+
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |  
+
*
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
+
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 
|-
 
|-
! style="background:#DCDCDC;" align="center" |[[Mastocytosis]]
+
! colspan="2" style="background:#DCDCDC;" align="center" |[[Lymphoma]]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
|
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="Left" |
 +
*
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |  
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |  
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |  
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |  
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |  
+
*
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |  
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |  
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 
|-
 
|-
! style="background:#DCDCDC;" align="center" |Drug induced [[enteritis]]
+
! colspan="2" style="background:#DCDCDC;" align="center" |[[Colorectal cancer]]
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |  
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |  
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |  
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |  
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
|
+
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |  
+
*
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |  
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |↑/↓
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*May be associated with FAP gene or HNPCC gene
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
|-
 +
! colspan="2" rowspan="5" style="background:#4479BA; color: #FFFFFF;" align="center" |Medication/Toxicity
 +
! colspan="2" style="background:#DCDCDC;" align="center" |Drug induced [[enteritis]]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
Line 852: Line 1,650:
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
|-
 
! style="background:#DCDCDC;" align="center" |[[Giardiasis]]
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |  
+
| style="padding: 5px 5px; background: #F5F5F5;" align="Left" |
 +
*
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
|
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
*
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |  
+
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |  
+
*
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
+
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |  
+
*
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
+
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |  
+
*
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
+
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 
|-
 
|-
! style="background:#DCDCDC;" align="center" |[[Strongyloidiasis]]
+
! colspan="2" style="background:#DCDCDC;" align="center" |[[Laxative abuse]]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
|
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="Left" |
 +
*
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |  
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |  
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |  
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |  
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |  
+
*
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |  
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |  
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 
|-
 
|-
! style="background:#DCDCDC;" align="center" |[[Tuberculosis]]
+
! colspan="2" style="background:#DCDCDC;" align="center" |[[Heavy metal ingestion]]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |  
+
| style="padding: 5px 5px; background: #F5F5F5;" align="Left" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
+
*
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
|
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
*
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |  
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |  
+
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |  
+
*
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |  
+
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
+
*
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |  
+
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
+
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 
|-
 
|-
! style="background:#DCDCDC;" align="center" |Chronic laxative abuse
+
! colspan="2" style="background:#DCDCDC;" align="center" |[[Organophosphate poisoning]]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
|
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="Left" |
 +
*
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
|-
 
! style="background:#DCDCDC;" align="center" | Pseudomembranous colitis
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |+
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |-
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |+
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |+/-
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |-
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |+
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |+
 
!
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |+/-
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
* Abdominal tenderness
 
* Presence of pseudomembranes of endoscopy
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
* Enzyme immunoassay (EIA) for ''C difficile'' toxin A and B
 
* Polymerase chain reaction (PCR) assay or ''C difficile'' antigen (glutamate dehydrogenase [GDH]) EIA
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |↑
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |↓
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |↓
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
* Leukocytosis
 
* Elevated serum creatinine
 
* Hypoalbuminemia
 
* Anasarca
 
* Elevated serum lactate
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
* Recent antibiotics use
 
* Recent surgery
 
* Colon cancer
 
* Diverticulitis
 
* Appendicitis
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
* Stool exam
 
* CT
 
|-
 
!
 
| colspan="10" |'''Clinical manifestation'''
 
! colspan="9" rowspan="3" |'''Lab findings'''
 
! rowspan="5" |Extra intestinal findings
 
! rowspan="5" |Cause/Pathogenesis
 
! rowspan="5" |Gold standard diagnosis
 
|-
 
! style="background:#DCDCDC;" align="center" |
 
! colspan="9" style="padding: 5px 5px; background: #F5F5F5;" align="center" |Symptoms
 
! rowspan="4" style="padding: 5px 5px; background: #F5F5F5;" align="left" |GI signs
 
|-
 
! style="background:#DCDCDC;" align="center" |
 
! colspan="2" rowspan="2" style="padding: 5px 5px; background: #F5F5F5;" align="center" |Duration
 
! colspan="3" rowspan="2" style="padding: 5px 5px; background: #F5F5F5;" align="center" |Diarrhea
 
! rowspan="3" style="padding: 5px 5px; background: #F5F5F5;" align="center" |Fever
 
! rowspan="3" style="padding: 5px 5px; background: #F5F5F5;" align="center" |Abdominal pain
 
!
 
! rowspan="3" style="padding: 5px 5px; background: #F5F5F5;" align="center" |Weight loss
 
|-
 
! style="background:#DCDCDC;" align="center" |
 
!
 
! colspan="5" style="padding: 5px 5px; background: #F5F5F5;" align="center" |Stool exam
 
| colspan="3" style="padding: 5px 5px; background: #F5F5F5;" align="center" |'''CBC'''
 
! rowspan="2" style="padding: 5px 5px; background: #F5F5F5;" align="left" |Other lab findings
 
|-
 
! style="background:#DCDCDC;" align="center" |
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |Acute
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |Chronic
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |Watery
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |Bloody
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |Fatty
 
!
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |WBC
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |RBC
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |Ova/Parasite
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |Osmotic gap
 
! style="padding: 5px 5px; background: #F5F5F5;" align="left" |Other
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |WBC
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |Hgb
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |Plt
 
|-
 
! style="background:#DCDCDC;" align="center" |CMV collitis
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |+
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |+
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |+/-
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |+
 
!
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |-
 
! style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
 
*
 
*
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |+/-
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |+
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |-
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |-
+
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
! style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
 
*
 
*
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |
+
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |-
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |-
 
! style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
*CD 4 level decreased as it is maily associated with HIV
 
! style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
 
*
 
*
! style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
*
 
*
! style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
*
 
*
 
|-
 
|-
! style="background:#DCDCDC;" align="center" |Macrobacterium Aviom Complex
+
! colspan="2" style="background:#DCDCDC;" align="center" |[[Opium withdrawal]]
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |+
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |+
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |+/-
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |+
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
!
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |-
+
| style="padding: 5px 5px; background: #F5F5F5;" align="Left" |
! style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
*
 
*
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |+/-
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |+
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |-
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |-
+
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
! style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
 
*
 
*
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |
+
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |-
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |-
 
! style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
*Immune system analysis may show defects
 
! style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
 
*
 
*
! style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
*
 
*
! style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
*
 
*
 
|-
 
|-
! style="background:#DCDCDC;" align="center" |Colon cancer
+
! colspan="2" rowspan="3" style="background:#4479BA; color: #FFFFFF;" align="center" |Iatrogenic
 +
! colspan="2" style="background:#DCDCDC;" align="center" |[[Short bowel syndrome]]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
* [[Abdominal distension|Abdominal distention]]
 +
* [[Tenderness (medicine)|Abdominal tenderness]]
 +
* Peripheral edema
 +
* [[Muscle atrophy]]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |+
+
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |↓
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | ↑
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
* [[Hypoalbuminemia]]
 +
* High level of [[Acute phase protein|acute phase reactant]]
 +
* Abnormal liver function tests
 +
* Low  vitamin A, B12, C,[[Vitamin D|D]], E, and K level
 +
* High [[fecal fat]]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
* Prior intestinal surgery
 +
 
 +
* [[Crohn's disease]]
 +
* [[Cancer|Malignancy]]
 +
* [[Radiation enteropathy|Radiation enteritis]]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
* Surgical intestinal resection
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |+
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |+
 
!
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |+
 
! style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
 
*
 
*
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |-
+
|-
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |+
+
! colspan="2" style="background:#DCDCDC;" align="center" |[[Radiation enteropathy|Radiation enteritis]]
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |-
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |-
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
! style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="Left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
*
 
*
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |-
+
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |↑/↓
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |-
 
! style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
*May be associated with FAP gene or HNPCC gene
 
! style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
 
*
 
*
! style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
*
 
*
! style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
*
 
*
 
|-
 
|-
! style="background:#DCDCDC;" align="center" |Intestinal metastasis
+
! colspan="2" style="background:#DCDCDC;" align="center" |[[Gastric dumping syndrome|Dumping syndrome]]
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |+
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |+
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |+
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
!
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |+
+
| style="padding: 5px 5px; background: #F5F5F5;" align="Left" |
! style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
 
*
 
*
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |-
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |+
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |-
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |-
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
! style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
*
 
*
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |↑/↓
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |↑/↓
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |↑/↓
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
! style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
*
 
*
! style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
*
 
*
! style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
*
 
*
! style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
*
 
*
 
|-
 
|-
! style="background:#DCDCDC;" align="center" |Infectious Diarrhea
+
! colspan="2" rowspan="4" style="background:#4479BA; color: #FFFFFF;" align="center" |Others
 +
! colspan="2" style="background:#DCDCDC;" align="center" |[[Abetalipoproteinemia]]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
* [[Abdominal distension]]
 +
* [[Visual field defect]]
 +
* [[Dysarthria]]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |+
+
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
* Low [[triglyceride]]
 +
* Low total [[cholesterol]] levels 
 +
* [[Acanthocytes]]
 +
* Low [[vitamin E]] levels
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
* Visual impairment
 +
* [[Ataxia]]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
* [[Autosomal recessive]] disorder caused by mutations encoding the [[microsomal]] [[triglyceride]] transfer protein (MTP)
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
* Clinical findings and low [[triglyceride]] and [[cholesterol]] level
 +
|-
 +
! colspan="2" style="background:#DCDCDC;" align="center" |[[Hyperthyroidism]]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |±
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | +
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
* Lump in the neck
 +
* [[Proptosis]]
 +
* [[Tremor]]
 +
* Increased [[Deep tendon reflex|DTR]]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |+
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |-
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |+
 
!
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |+/-
 
! style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
 
*
 
*
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |+
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |+
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |-
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |-
+
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
! style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+
* Elevated [[T4]]
*Stool culture may be positive for responsible organism
+
* Elevated [[T3]]
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |
+
* Decreased [[TSH]]
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |-
+
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |-
+
* Lid lag
! style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+
* [[Sweating]]
 +
* [[Hyperpigmentation]]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
* [[Graves' disease]]
 +
* [[Hashimoto's thyroiditis]]
 +
* [[Toxic adenoma]]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
* [[TSH]]
 +
|-
 +
! colspan="2" style="background:#DCDCDC;" align="center" |[[Diabetic neuropathy]]
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="Left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
*
 
*
! style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
*
 
*
! style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
*Trichuris trichiura infection
 
*EHEC
 
*Entamoeba
 
*Intestinal amebiasi
 
! style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
 
*
 
*
 
|-
 
|-
! style="background:#DCDCDC;" align="center" |Infectious Diarrhea
+
! colspan="2" style="background:#DCDCDC;" align="center" |[[Scleroderma|Systemic sclerosis]]
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |+
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |+
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |+
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |+
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
!
+
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |-
+
| style="padding: 5px 5px; background: #F5F5F5;" align="Left" |
! style="padding: 5px 5px; background: #F5F5F5;" align="left" |
+
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | -
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
*
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |
 +
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
*
 
*
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |+
+
| style="padding: 5px 5px; background: #F5F5F5;" align="left" |
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |+
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |-
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |-
 
! style="padding: 5px 5px; background: #F5F5F5;" align="left" |
 
*Stool culture may be positive for responsible organism
 
! style="padding: 5px 5px; background: #F5F5F5;" align="center" |↑
 
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*
 
*
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+
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*
 
*
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+
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*Campylobacter
 
*Escherischia coli enterohemmorrhagic
 
*Clostridium Perfringens
 
*Salmonellosis
 
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*
 
*
|-
 
!Isosporiasis
 
!
 
!+
 
!
 
!+
 
!
 
!
 
!+
 
!
 
!-
 
!
 
!+
 
!+
 
!-
 
!-
 
!
 
!↑
 
!-
 
!
 
!
 
!
 
!
 
!
 
|-
 
!Parasitic Diarrhea
 
!+
 
!+
 
!
 
!+
 
!
 
!-
 
!+
 
!
 
!+/-
 
!
 
!+
 
!+
 
!+
 
!-
 
!
 
!↑
 
!-
 
!-
 
!
 
!
 
!Amebiasis
 
Intestinal Schistosomiasis
 
 
Balantidiasis
 
 
Trichuriasis
 
!
 
 
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|- }
 
|}
 
|}

Latest revision as of 21:49, 12 December 2017

Diarrhea

Abbreviations: GI: Gastrointestinal, WBC: White blood cells, Plt: Platelets, Hgb: Hemoglobin, IgE: Immunoglobulin E, IgA: Immunoglobulin A, ETEC: Escherichia coli enteritis, EPEC: Enteropathogenic Escherichia coli, EIEC: Enteroinvasive Escherichia coli, EHEC: Enterohemorrhagic Escherichia coli, EAEC: Enteroaggregative Escherichia coli, ESR: Erythrocyte sedimentation rate, CRP: C-reactive protein,

Categories Cause Clinical manifestation Lab findings Extra intestinal findings Cause/Pathogenesis Gold standard diagnosis
Symptoms GI signs
Duration Diarrhea Fever Abdominal pain Weight loss
Stool exam CBC Other lab findings
Acute Chronic Watery Bloody Fatty WBC RBC Ova/Parasite Osmotic gap Other WBC Hgb Plt
Gastrointestinal Crohns disease - + + + + ± + + + + - - -
  • Abnormal immune response to self antigens
Ulcerative colitis - + + + + + + +
  • Normal in mild cases
+ + - - -
  • Abnormal immune response to self antigens
Celiac disease - + ± - ± - + + - -
- -
  • IgA endomysial antibody
  • Anti-tissue transglutaminase antibody
  • Anti-gliadin antibody
  • IgA endomysial antibody
  • IgA tissue transglutaminase antibody
Cystic fibrosis - + - - + ± + +
- -
- -
  • Positive DNA analysis for CFTR
  • Nasal transepithelial potential difference
Chronic pancreatitis - + + - + - + + - -
- - -
  • Slightly elevated amylase and lipase
  • Abnormal pancreatic function test
  • Repeated acute pancreatitis
  • Alcohol abuse
  • Genetic
  • Autoimmune
Bile acid malabsorption
Microscopic colitis - + + + - - + + - -
- -
Infective colitis -
- -
Ischemic colitis -
- -
Mesenteric ischemia -
- -
Lactose intolerance + + + - - - + - -
- - -
Irritable bowel syndrome - + ± - ± - ± - - -
- - -
  • Diagnosis of exclusion
Infection Bacterial Whipple's disease - + + - + ± + + - - - - ↓/↑
Tropical sprue + + + - + + + + - -
- -
  • Diagnosis of exclusion
Small bowel bacterial overgrowth - + + - + - + + - -
- -
  • Excess bacteria in the small intestine
  • Alterations in intestinal anatomy or GI motility, 
  • Lack of gastric acid secretion
  • Diagnosis of exclusion
Food poisoning -
- -
Pseudomembranous colitis + - + +/- - + + +/-
  • Abdominal tenderness
  • Presence of pseudomembranes of endoscopy
- -
  • Enzyme immunoassay (EIA) for C difficile toxin A and B
  • Polymerase chain reaction (PCR) assay or C difficile antigen (glutamate dehydrogenase [GDH]) EIA
  • Leukocytosis
  • Elevated serum creatinine
  • Hypoalbuminemia
  • Anasarca
  • Elevated serum lactate
  • Recent antibiotics use
  • Recent surgery
  • Colon cancer
  • Diverticulitis
  • Appendicitis
  • Stool exam
  • CT
Shigella -
- -
Salmonella -
- -
Campylobacter jejuni -
- -
E-coli ETEC

(Traveler's diarrhea)

+ - + - - + - -
- -
  • Enterotoxins:
    • Heat-labile enterotoxin (LT) 
    • Heat-stable enterotoxin (ST)
  • Enterotoxins:
    • Heat-labile enterotoxin (LT)  Heat-stable enterotoxin (ST)
EPEC -
- -
EIEC -
- -
EHEC -
- -
EAEC -
- -
Yersinia enterocolitica -
- -
Vibrio cholera -
- -
Aeromonas -
- -
Plesiomonas -
- -
Mycobacterium avium complex + + +/- + -
+/- + - -
- -
  • Immune system analysis may show defects
Other infections
  • aaaa
  • bbbb
+ + - + +/-
+ + - -
  • Stool culture may be positive for responsible organism
- -
Virus Rotavirus -
- -
Echovirus -
- -
Adenovirus -
- -
Norovirus -
- -
CMV colitis + + +/- + -
+/- + - -
- -
  • CD 4 level decreased as it is maily associated with HIV
HIV -
- -
Hepatitis Hepatitis A -
- -
Hepatitis E -
- -
Parasite Entamoeba histolytica -
+ -
Giardia -
+ -
Cryptosporidium -
+ -
Microsporidia -
+ -
Isospora + + + -
+ + + -
-
Other Parasitic diarrhea
  • aaaa
  • bbbb
+ + + - + +/-
+ + + -
- -
Tumors Carcinoid tumor -
-
VIPoma + + + - + - + + -
- - -
  • Primary secretory tumor
  • Elevated VIP levels
  • Followed by imaging
Zollinger-Ellison syndrome - + + - + - + + -
- -
  • Elevated basal or stimulated serum gastrin> 120 pg/mL
Somatostatinoma -
-
Lymphoma -
- -
Colorectal cancer + + + +
- + - -
- ↑/↓ -
  • May be associated with FAP gene or HNPCC gene
Medication/Toxicity Drug induced enteritis -
- -
Laxative abuse -
-
Heavy metal ingestion -
- -
Organophosphate poisoning -
- -
Opium withdrawal -
- -
Iatrogenic Short bowel syndrome + + + - + - - + - -
-
  • Prior intestinal surgery
  • Surgical intestinal resection
Radiation enteritis -
- -
Dumping syndrome -
- -
Others Abetalipoproteinemia - + + - + - + + - -
- - -
Hyperthyroidism - + + - - ± + + - -
- - -
  • Elevated T4
  • Elevated T3
  • Decreased TSH
Diabetic neuropathy -
- -
Systemic sclerosis -
- -

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