Difference between revisions of "Polo kinase"
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Latest revision as of 17:58, 26 December 2007
- ATP + a protein ADP + a phosphoprotein
This enzyme belongs to the family of transferases, specifically those transferring a phosphate group to the sidechain oxygen atom of serine or threonine residues in proteins (protein-serine/threonine kinases). The systematic name of this enzyme class is ATP:protein phosphotransferase (spindle-pole-dependent). Other names in common use include Cdc5, Cdc5p, Plk, PLK, Plk1, Plo1, POLO kinase, polo serine-threonine kinase, polo-like kinase, polo-like kinase 1, serine/threonine-specific Drosophila kinase polo, and STK21. This enzyme participates in 3 metabolic pathways: cell cycle, cell cycle - yeast, and progesterone-mediated oocyte maturation.
- IUBMB entry for 184.108.40.206
- BRENDA references for 220.127.116.11 (Recommended.)
- PubMed references for 18.104.22.168
- PubMed Central references for 22.214.171.124
- Google Scholar references for 126.96.36.199
- C, Karess RE, Glover DM, Sunkel CE (1991). "polo encodes a protein kinase homolog required for mitosis in Drosophila". Genes. Dev. 5: 2153&ndash, 65. PMID 1660828.
- Golsteyn RM, Mundt KE, Fry AM, Nigg EA (1995). "Cell cycle regulation of the activity and subcellular localization of Plk1, a human protein kinase implicated in mitotic spindle function". J. Cell. Biol. 129: 1617&ndash, 28. PMID 7790358.
- Mulvihill DP, Hyams JS (2002). "Cytokinetic actomyosin ring formation and septation in fission yeast are dependent on the full recruitment of the polo-like kinase Plo1 to the spindle pole body and a functional spindle assembly checkpoint". J. Cell. Sci. 115: 3575&ndash, 86. PMID 12186944.
- Ohkura H (2003). "Phosphorylation: polo kinase joins an elite club". Curr. Biol. 13: R912&ndash, 4. PMID 14654016.
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