Isonocardicin synthase

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In enzymology, an isonocardicin synthase (EC is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + nocardicin E 5'-methylthioadenosine + isonocardicin A

Thus, the two substrates of this enzyme are S-adenosyl-L-methionine and nocardicin E, whereas its two products are 5'-methylthioadenosine and isonocardicin A.

This enzyme belongs to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. The systematic name of this enzyme class is S-adenosyl-L-methionine:nocardicin-E 3-amino-3-carboxypropyltransferase. This enzyme is also called nocardicin aminocarboxypropyltransferase.


  • IUBMB entry for
  • BRENDA references for (Recommended.)
  • PubMed references for
  • PubMed Central references for
  • Google Scholar references for
  • CA (1988). "Cell-free biosynthesis of nocardicin A from nocardicin E and S-adenosylmethionine". J. Am. Chem. Soc. 110: 8238&ndash, 8239.

External links

The CAS registry number for this enzyme class is 118246-74-5.

Gene Ontology (GO) codes