Difference between revisions of "HLA-B*83"

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'''HLA-B*83''' (B83) is an [[Human leukocyte antigen|HLA]]-[[HLA-B|B]] [[allele]]-group composed of a single [[allele]], B*8301. There is no useful [[serology]] associated with this allele.<ref name="pmid15787720">{{cite journal | author = Marsh SG, Albert ED, Bodmer WF, ''et al'' | title = Nomenclature for factors of the HLA system, 2004 | journal = Tissue Antigens | volume = 65 | issue = 4 | pages = 301–69 | year = 2005 | pmid = 15787720 | doi = 10.1111/j.1399-0039.2005.00379.x}}</ref> It is found in a single Mbenzele Pygmy tribe of the Central Africa Republic at 1.5%.<ref name="pmid12956877">{{cite journal | author = Bruges Armas J, Destro-Bisol G, López-Vazquez A, ''et al'' | title = HLA class I variation in the West African [[pygmy|Pygmies]] and their genetic relationship with other African populations | journal = Tissue Antigens | volume = 62 | issue = 3 | pages = 233–42 | year = 2003 | pmid = 12956877 | doi = }}</ref> ''B*8301 appears to be the result of the replacement of exon 2 from B*4402 with exon 2 from B*5603''.<ref name="pmid11380952">{{cite journal | author = Steiner NK, Gans CP, Kosman C, ''et al'' | title = New alleles in the B44 family including B*44022, B*44032, B*4411, B*4420, B*4421, B*4424, and B*8301 | journal = Tissue Antigens | volume = 57 | issue = 4 | pages = 376–9 | year = 2001 | pmid = 11380952 | doi = }}</ref>
{{context}}'''HLA-B*83''' (B83) is an [[Human leukocyte antigen|HLA]]-[[HLA-B|B]] [[allele]]-group composed of a single [[allele]], B*8301. There is no useful [[serology]] associated with this allele.<ref name="pmid15787720">{{cite journal | author = Marsh SG, Albert ED, Bodmer WF, ''et al'' | title = Nomenclature for factors of the HLA system, 2004 | journal = Tissue Antigens | volume = 65 | issue = 4 | pages = 301–69 | year = 2005 | pmid = 15787720 | doi = 10.1111/j.1399-0039.2005.00379.x}}</ref> It is found in a single [[Pygmies#Groups|Mbenzele Pygmy]] tribe of the [[Central Africa Republic]] at 1.5%.<ref name="pmid12956877">{{cite journal | author = Bruges Armas J, Destro-Bisol G, López-Vazquez A, ''et al'' | title = HLA class I variation in the West African [[pygmy|Pygmies]] and their genetic relationship with other African populations | journal = Tissue Antigens | volume = 62 | issue = 3 | pages = 233–42 | year = 2003 | pmid = 12956877 | doi = }}</ref> ''B*8301 appears to be the result of the replacement of exon 2 from [[HLA-B44|B*4402]] with exon 2 from [[HLA-B56|B*5603]]''.<ref name="pmid11380952">{{cite journal | author = Steiner NK, Gans CP, Kosman C, ''et al'' | title = New alleles in the B44 family including B*44022, B*44032, B*4411, B*4420, B*4421, B*4424, and B*8301 | journal = Tissue Antigens | volume = 57 | issue = 4 | pages = 376–9 | year = 2001 | pmid = 11380952 | doi = }}</ref>
 
  
 
[[Image:LocationCentralAfricanRepublic.svg|left|thumb|200px|Location of Central African Republic]]
 
[[Image:LocationCentralAfricanRepublic.svg|left|thumb|200px|Location of Central African Republic]]
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Latest revision as of 15:45, 9 August 2012


major histocompatibility complex (human), class I, B*83
Alleles B*8301
Structure (See HLA-B)
Symbol(s) HLA-B
EBI-HLA B*8301
Locus chr.6 6p21.31

HLA-B*83 (B83) is an HLA-B allele-group composed of a single allele, B*8301. There is no useful serology associated with this allele.[1] It is found in a single Mbenzele Pygmy tribe of the Central Africa Republic at 1.5%.[2] B*8301 appears to be the result of the replacement of exon 2 from B*4402 with exon 2 from B*5603.[3]

Location of Central African Republic
Location of Africa's Pygmy Tribes



















References

  1. Marsh SG, Albert ED, Bodmer WF; et al. (2005). "Nomenclature for factors of the HLA system, 2004". Tissue Antigens. 65 (4): 301–69. doi:10.1111/j.1399-0039.2005.00379.x. PMID 15787720.
  2. Bruges Armas J, Destro-Bisol G, López-Vazquez A; et al. (2003). "Pygmies". Tissue Antigens. 62 (3): 233–42. PMID 12956877.
  3. Steiner NK, Gans CP, Kosman C; et al. (2001). "New alleles in the B44 family including B*44022, B*44032, B*4411, B*4420, B*4421, B*4424, and B*8301". Tissue Antigens. 57 (4): 376–9. PMID 11380952.



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