Difference between revisions of "Glutamate formimidoyltransferase"

Jump to: navigation, search
m (Robot: Automated text replacement (-(?ms)^(.*)$ +\1 {{WikiDoc Sources}}))
m (Robot: Automated text replacement (-{{WikiDoc Cardiology Network Infobox}} +, -<references /> +{{reflist|2}}, -{{reflist}} +{{reflist|2}}))
 
Line 8: Line 8:
  
 
==References==
 
==References==
{{reflist}}
+
{{reflist|2}}
  
 
==External links==
 
==External links==

Latest revision as of 17:53, 4 September 2012

Glutamate formimidoyltransferase is a methyltransferase enzyme which uses tetrahydrofolate as part of histidine catabolism. It catalyses two reactions:

  • 5-formimidoyltetrahydrofolate + L-glutamate <=> tetrahydrofolate + N-formimidoyl-L-glutamate
  • 5-formyltetrahydrofolate + L-glutamate <=> tetrahydrofolate + N-formyl-L-glutamate

It is classified under EC 2.1.2.5 and in mammals is found as part of a bifunctional enzyme that also has formimidoyltetrahydrofolate cyclodeaminase activity.[1]

References

  1. MacKenzie RE, Aldridge M, Paquin J (1980). "The bifunctional enzyme formiminotransferase-cyclodeaminase is a tetramer of dimers". J. Biol. Chem. 255 (19): 9474–8. PMID 7410436.

External links


Linked-in.jpg