- ATP + NH3 + CO2 ADP + carbamoyl phosphate
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with a carboxy group as acceptor. The systematic name of this enzyme class is ATP:carbamate phosphotransferase. Other names in common use include CKase, carbamoyl phosphokinase, and carbamyl phosphokinase. This enzyme participates in 4 metabolic pathways: purine metabolism, glutamate metabolism, arginine and proline metabolism, and nitrogen metabolism.
- IUBMB entry for 126.96.36.199
- BRENDA references for 188.8.131.52 (Recommended.)
- PubMed references for 184.108.40.206
- PubMed Central references for 220.127.116.11
- Google Scholar references for 18.104.22.168
- Bishop SH, Grisolia S (1966). "Crystalline carbamate kinase". Biochim. Biophys. Acta. 118: 211&ndash, 5. PMID 4959296.
- Davis RH (1965). "Carbamyl phosphate synthesis in Neurospora crassa. I. Preliminary characterization of arginine-specific carbamyl phosphokinase". Biochim. Biophys. Acta. 107: 44&ndash, 53. PMID 5857367.
- Glasziou KT (1956). "The metabolism of arginine in Serratia marcescens. II Carbamyladenosine diphosphate phosphoferase". Aust. J. Biol. Sci.: 253&ndash, 262.
- Jones ME, Spector L and Lipmann F (1955). "Carbamyl phosphate, the carbamyl donor in enzymatic citrulline synthesis". J. Am. Chem. Soc. 77: 819&ndash, 820.
- Srivenugopal KS, Adiga PR (1981). "Enzymic conversion of agmatine to putrescine in Lathyrus sativus seedlings. Purification and properties of a multifunctional enzyme (putrescine synthase)". J. Biol. Chem. 256: 9532&ndash, 41. PMID 6895223.
- The CAS registry number for this enzyme class is 9026-69-1.
Gene Ontology (GO) codes
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