Zipeprol

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Zipeprol
Zipeprol.png
Clinical data
AHFS/Drugs.comInternational Drug Names
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administration
Oral
ATC code
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UNII
KEGG
E number{{#property:P628}}
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Chemical and physical data
FormulaC23H32N2O3
Molar mass384.512 g/mol
3D model (JSmol)
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Zipeprol is a centrally acting cough suppressant developed in France in the 1970s.[1] It is not an morphinan derivative (in contrast to codeine and dextromethorphan). Zipeprol acts as a local anaesthetic and has mucolytic, antihistamine and anticholinergic properties.[2]It is sold with several brand names such as Zinolta and Respilene. It is not available in the United States or Canada and has been discontinued in Europe. It is still available in some countries in Asia and South America.

Zipeprol has been misused in Korea, mainly for the hallucinations it produces. Such use has become an issue due to the seizures and various neurological side effects it causes at high dosages.[3]

References

  1. Patent US 3718650, Mauvernay,RY, "New Derivatives of Substituted Piperazines", issued 1973-02-27 
  2. PMID 8057 (PMID 8057)
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  3. PMID 15542749 (PMID 15542749)
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