VMAT1

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solute carrier family 18 (vesicular monoamine), member 1
Identifiers
SymbolSLC18A1
Alt. symbolsVMAT1, VAT1
Entrez6570
HUGO10934
OMIM193002
RefSeqNM_003053
UniProtP54219
Other data
LocusChr. 8 p21.3

For norepinephrine to be acted upon by PNMT in the cytosol, it must first be shipped out of granules of the chromaffin cells. This may occur via the catecholamine-H+ exchanger VMAT1.

VMAT1 is also responsible for transporting newly synthesized epinephrine from the cytosol back into chromaffin granules in preparation for release.

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