VIPoma history and symptoms

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VIPoma Microchapters

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Patient Information

Overview

Historical Perspective

Pathophysiology

Causes

Differentiating VIPoma from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

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Case #1

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Madhu Sigdel M.B.B.S.[2]Parminder Dhingra, M.D. [3]

Overview

The hallmark of VIPoma is watery diarrhea. A positive history of abdominal pain, weight loss, numbness, and weakness is suggestive of VIPoma

History

Patients with VIPoma may have a positive history of:

Symptoms

Common Symptoms

Symptoms of VIPoma usually arise when tumor reaches certain size. Most tumors are > 2cm and metastatic by the time symptoms arise. Common symptoms may include any of the following:[1][2][3][4]

Less Common Symptoms

References

  1. VIPoma. U.S. National Library of Medicine. Accessed on October 23, 2015. https://www.nlm.nih.gov/medlineplus/ency/article/000228.htm
  2. Remme CA, de Groot GH, Schrijver G (2006). "Diagnosis and treatment of VIPoma in a female patient.". Eur J Gastroenterol Hepatol. 18 (1): 93–9. PMID 16357627. 
  3. Ghaferi AA, Chojnacki KA, Long WD, Cameron JL, Yeo CJ (2008). "Pancreatic VIPomas: subject review and one institutional experience.". J Gastrointest Surg. 12 (2): 382–93. PMID 17510774. doi:10.1007/s11605-007-0177-0. 
  4. Ito T, Igarashi H, Jensen RT (2012). "Pancreatic neuroendocrine tumors: clinical features, diagnosis and medical treatment: advances.". Best Pract Res Clin Gastroenterol. 26 (6): 737–53. PMC 3627221Freely accessible. PMID 23582916. doi:10.1016/j.bpg.2012.12.003. 

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