Ureidoglycolate lyase

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In enzymology, an ureidoglycolate lyase (EC is an enzyme that catalyzes the chemical reaction

(S)-ureidoglycolate glyoxylate + urea

Hence, this enzyme has one substrate, (S)-ureidoglycolate, and two products, glyoxylate and urea.

This enzyme belongs to the family of lyases, specifically amidine lyases. The systematic name of this enzyme class is (S)-ureidoglycolate urea-lyase (glyoxylate-forming). Other names in common use include ureidoglycolatase, ureidoglycolase, ureidoglycolate hydrolase, and (S)-ureidoglycolate urea-lyase. This enzyme participates in purine metabolism.


  • IUBMB entry for
  • BRENDA references for (Recommended.)
  • PubMed references for
  • PubMed Central references for
  • Google Scholar references for
  • Trijbels F, Vogels GD (1967). "Allantoate and ureidoglycolate degradation by Pseudomonas aeruginosa". Biochim. Biophys. Acta. 132: 115&ndash, 26. PMID 6030341.

External links

The CAS registry number for this enzyme class is 9014-57-7.

Gene Ontology (GO) codes