UBE2O

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Identifiers
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External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
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RefSeq (mRNA)

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Ubiquitin-conjugating enzyme E2 O is a protein that in humans is encoded by the UBE2O gene.[1][2][3] UBE2O functions during terminal erythroid differentiation to eliminate generic cellular components in parallel with abundant synthesis of hemoglobin.[4]

References

  1. Yokota T, Nagai H, Harada H, Mine N, Terada Y, Fujiwara H, Yabe A, Miyazaki K, Emi M (Apr 2001). "Identification, tissue expression, and chromosomal position of a novel gene encoding human ubiquitin-conjugating enzyme E2-230k". Gene. 267 (1): 95–100. doi:10.1016/S0378-1119(01)00407-3. PMID 11311559.
  2. Nagase T, Kikuno R, Hattori A, Kondo Y, Okumura K, Ohara O (Feb 2001). "Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (6): 347–55. doi:10.1093/dnares/7.6.347. PMID 11214970.
  3. "Entrez Gene: UBE2O ubiquitin-conjugating enzyme E2O".
  4. Nguyen AT, Prado MA, et al. (2017). "UBE2O remodels the proteome during terminal erythroid differentiation". Science. 357 (6350): eaan0218. doi:10.1126/science.aan0218. PMID 28774900.

Further reading




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