Tuberous sclerosis natural history, complications and prognosis

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Tuberous sclerosis Microchapters

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Differentiating Tuberous sclerosis from other Diseases

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Natural History, Complications and Prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Natural History, Complications, Prognosis

Natural History

  • Those individuals with mild symptoms generally do well and live long productive lives, while individuals with the more severe form may have serious disabilities.
  • However, with appropriate medical care, most individuals with the disorder can look forward to normal life expectancy.

Complications

Prognosis

  • The prognosis for individuals with TSC depends on the severity of symptoms, which range from mild skin abnormalities to varying degrees of learning disabilities and epilepsy to severe mental retardation, uncontrollable seizures, and kidney failure.

References

  1. Rakowski SK, Winterkorn EB, Paul E, Steele DJ, Halpern EF, Thiele EA. (2006). "Renal manifestations of tuberous sclerosis complex: Incidence, prognosis, and predictive factors". Kidney International. PMID 17003820.
  2. Shepherd C, Gomez M, Lie J, Crowson C (1991). "Causes of death in patients with tuberous sclerosis". Mayo Clin Proc. 66 (8): 792–6. PMID 1861550.

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