Triglucosylalkylacylglycerol sulfotransferase

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In enzymology, a triglucosylalkylacylglycerol sulfotransferase (EC 2.8.2.19) is an enzyme that catalyzes the chemical reaction

3'-phosphoadenylyl sulfate + alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,3-1-O- alkyl-2-O-acylglycerol adenosine 3',5'-bisphosphate + 6-sulfo-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,6-alpha-D-glucosyl- 1,3-1-O-alkyl-2-O-acylglycerol

The 3 substrates of this enzyme are 3'-phosphoadenylyl sulfate, alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,3-1-O-, and alkyl-2-O-acylglycerol, whereas its 3 products are adenosine 3',5'-bisphosphate, 6-sulfo-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,6-alpha-D-glucosyl-, and 1,3-1-O-alkyl-2-O-acylglycerol.

This enzyme belongs to the family of transferases, specifically the sulfotransferases, which transfer sulfur-containing groups. The systematic name of this enzyme class is 3'-phosphoadenylyl-sulfate:triglucosyl-1-O-alkyl-2-O-acylglycerol 6-sulfotransferase. This enzyme is also called triglucosylmonoalkylmonoacyl sulfotransferase.

References

  • IUBMB entry for 2.8.2.19
  • BRENDA references for 2.8.2.19 (Recommended.)
  • PubMed references for 2.8.2.19
  • PubMed Central references for 2.8.2.19
  • Google Scholar references for 2.8.2.19
  • Liau YH, Zdebska E, Slomiany A, Slomiany BL (1982). "Biosynthesis in vitro of a sulfated triglucosyl monoalkylmonoacylglycerol by rat gastric mucosa". J. Biol. Chem. 257: 12019&ndash, 23. PMID 6956577.

External links

The CAS registry number for this enzyme class is 83589-05-3.

Gene Ontology (GO) codes


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