Treosulfan

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Treosulfan
Treosulfan.png
Clinical data
Synonyms1,2,3,4-Butanetetrol, 1,4-dimethanesulfonate, Threitol 1,4-dimethanesulfonate, Threitol 1,4-bismethanesulfonate; L-Threitol 1,4-bis(methanesulfonate); Ovastat; Threosulphan; Treosulphan; Tresulfan
AHFS/Drugs.comInternational Drug Names
Routes of
administration
Oral, IV
ATC code
Identifiers
CAS Number
PubChem CID
UNII
E number{{#property:P628}}
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Chemical and physical data
FormulaC6H14O8S2
Molar mass278.30056 g·mol−1
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List of terms related to Treosulfan

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Treosulfan is a substance that is being studied in the treatment of cancer.[1] It belongs to the family of drugs called alkylating agents. It has been used mainly as a substitute of busulfan in frail patients, as the side effects and toxicity are supposedly less severe.

References

  1. Schmittel A, Schmidt-Hieber M, Martus P; et al. (December 2006). "A randomized phase II trial of gemcitabine plus treosulfan versus treosulfan alone in patients with metastatic uveal melanoma". Ann. Oncol. 17 (12): 1826–9. doi:10.1093/annonc/mdl309. PMID 16971664.

External links

  • Treosulfan entry in the public domain NCI Dictionary of Cancer Terms

 This article incorporates public domain material from the U.S. National Cancer Institute document "Dictionary of Cancer Terms".


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