TRPM6

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Transient receptor potential cation channel, subfamily M, member 6
Identifiers
Symbol(s) TRPM6; CHAK2; HMGX; HOMG; HSH
External IDs OMIM: 607009 MGI2675603 Homologene9767
RNA expression pattern

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More reference expression data

Orthologs
Human Mouse
Entrez 140803 225997
Ensembl ENSG00000119121 ENSMUSG00000024727
Uniprot Q9BX84 Q8CIR4
Refseq NM_017662 (mRNA)
NP_060132 (protein)
XM_987699 (mRNA)
XP_992793 (protein)
Location Chr 9: 76.53 - 76.69 Mb Chr 19: 18.82 - 18.96 Mb
Pubmed search [1] [2]

TRPM6 is a transient receptor potential ion channel associated with hypomagnesemia with secondary hypocalcemia.[1]



See also

References

  1. Schlingmann KP, Weber S, Peters M; et al. (2002). "Hypomagnesemia with secondary hypocalcemia is caused by mutations in TRPM6, a new member of the TRPM gene family". Nat. Genet. 31 (2): 166–70. PMID 12032568. doi:10.1038/ng889. 

Further reading

  • Chubanov V, Gudermann T, Schlingmann KP (2006). "Essential role for TRPM6 in epithelial magnesium transport and body magnesium homeostasis.". Pflugers Arch. 451 (1): 228–34. PMID 16075242. doi:10.1007/s00424-005-1470-y. 
  • Clapham DE, Julius D, Montell C, Schultz G (2006). "International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels.". Pharmacol. Rev. 57 (4): 427–50. PMID 16382100. doi:10.1124/pr.57.4.6. 
  • Bödding M (2007). "TRPM6: A Janus-like protein.". Handb Exp Pharmacol (179): 299–311. PMID 17217065. doi:10.1007/978-3-540-34891-7_18. 
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External links

Template:Membrane-protein-stub This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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