T2-induced deoxynucleotide kinase

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In enzymology, a T2-induced deoxynucleotide kinase (EC 2.7.4.12) is an enzyme that catalyzes the chemical reaction

ATP + dGMP (or dTMP) ADP + dGDP (or dTDP)

The 3 substrates of this enzyme are ATP, dGMP, and dTMP, whereas its 3 products are ADP, dGDP, and dTDP.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with a phosphate group as acceptor. The systematic name of this enzyme class is ATP:(d)NMP phosphotransferase.

References

  • IUBMB entry for 2.7.4.12
  • BRENDA references for 2.7.4.12 (Recommended.)
  • PubMed references for 2.7.4.12
  • PubMed Central references for 2.7.4.12
  • Google Scholar references for 2.7.4.12
  • BELLO LJ, BESSMAN MJ (1963). "The enzymology of virus-infected bacteria. IV. Purification and properties of the deoxynucleotide kinase induced by bacteriophage T2". J. Biol. Chem. 238: 1777&ndash, 87. PMID 13967158.

External links

The CAS registry number for this enzyme class is 37278-99-2.

Gene Ontology (GO) codes



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