Survival of motor neuron

Jump to: navigation, search
survival of motor neuron 1, telomeric
Identifiers
SymbolSMN1
Alt. symbolsSMA@, SMA
Entrez6606
HUGO11117
OMIM600354
RefSeqNM_000344
UniProtQ16637
Other data
LocusChr. 5 q13
survival of motor neuron 2, centromeric
Identifiers
SymbolSMN2
Entrez6607
HUGO11118
OMIM601627
RefSeqNM_017411
UniProtQ16637
Other data
LocusChr. 5 q13

Survival of motor neuron is a protein associated with spinal muscular atrophy.

A 2004 study using high-throughput screening found indoprofen to increase production of the survival of motor neuron protein, suggesting it may provide insight into treatments for spinal muscular atrophies.[1]

See also

References

  1. Lunn MR, Root DE, Martino AM; et al. (2004). "Indoprofen upregulates the survival motor neuron protein through a cyclooxygenase-independent mechanism". Chem Biol. 11 (11): 1489–93. doi:10.1016/j.chembiol.2004.08.024. PMID 15555999.

External links


Linked-in.jpg