Sulfatase

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Identifiers
SymbolSulfatase
PfamPF00884
InterProIPR000917
PROSITEPDOC00117
SCOP1auk
SUPERFAMILY1auk
OPM superfamily24
OPM protein1p49

Sulfatases EC 3.1.6. are esterase enzymes which remove sulfate from a variety of substrates by hydrolyzing various sulphate esters.

The following sulphatases were shown to be structurally related based on their sequence homology[1][2],[3],

Human proteins containing this domain

ARSA; ARSB; ARSD; ARSE; ARSF; ARSG; ARSH; ARSI; ARSJ; ARSK; GALNS; GNS; IDS; PIGG; SGSH; STS; SULF1; SULF2;

References

  1. von Figura K, Vingron M, Schmidt B, Meyer HE, Peters C, Rommerskirch W, Rupp K, Pohlmann R, Zuhlsdorf M (1990). "Phylogenetic conservation of arylsulfatases. cDNA cloning and expression of human arylsulfatase B". J. Biol. Chem. 265 (6): 3374–3381. PMID 2303452.
  2. Wilson PJ, Morris CP, Anson DS, Occhiodoro T, Bielicki J, Clements PR, Hopwood JJ (1990). "Hunter syndrome: isolation of an iduronate-2-sulfatase cDNA clone and analysis of patient DNA". Proc. Natl. Acad. Sci. U.S.A. 87 (21): 8531–8535. PMID 2122463.
  3. Grossman AR, de Hostos EL, Schilling J (1989). "Structure and expression of the gene encoding the periplasmic arylsulfatase of Chlamydomonas reinhardtii". Mol. Gen. Genet. 218 (2): 229–239. PMID 2476654.

External links

This article incorporates text from the public domain Pfam and InterPro: IPR000917

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