Seminal vesicle

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Seminal vesicle
Male anatomy.png
Male Anatomy
Prostate with seminal vesicles and seminal ducts, viewed from in front and above.
Latin vesiculæ seminales
Gray's subject #260 1246
Artery Inferior vesical artery, middle rectal artery
Lymph external iliac lymph nodes, internal iliac lymph nodes
Precursor Wolffian duct
MeSH Seminal+Vesicles

The seminal vesicles are a pair of simple tubular glands posteroinferior to the urinary bladder of males.


They are approximately 5 cm in length, though the full length of the gland is approximately 10 cm and curled up inside of the structure. Both glands form as an outpocketing of the wall of the ampulla of the vas deferens.

The ducts of the seminal vesicles open into the vas deferens as it enters the prostate gland.


They secrete a significant proportion of the fluid that ultimately becomes semen. About 70% of the seminal fluid in humans originates from the seminal vesicles.

The thick secretions contain proteins, enzymes, fructose, mucus, vitamin C, flavins, phosphorylcholine and prostaglandins. The high fructose concentrations provide nutrient energy for the spermatozoa as they travel through the female reproductive system. The fluid is expelled under sympathetic contraction of the muscularis muscle coat.


Histologically, the seminal vesicles are defined by their tortuous pathways, false lumens, pseudo-stratified columnar epithelium and cuboidal cells along the basal layer.

The height of these columnar cells, and therefore activity, is dependent upon testosterone levels in the blood.

The lumen is large and stores the fluid secretions between ejaculations.

The mucosa is arranged into convoluted folds, significantly increasing surface area.

Joining the epithelium to the underlying muscularis is a fibroelastic connective tissue layer, with the well-developed muscularis layer composed of an inner circular and outer longitudinal layer of smooth muscle.

Additional images

External links

cs:Semenný váček da:Sædblære de:Samenblase id:Vesikula seminalis it:Vescicola seminale lt:Sėklinės pūslelės nl:Zaadblaas simple:Seminal vesicle sk:Semenný mechúrik fi:Rakkularauhanen sv:Sädesblåsa