SMC1B

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External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
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RefSeq (mRNA)

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Structural maintenance of chromosomes protein 1B (SMC-1B) is a protein that in humans is encoded by the SMC1B gene.[1][2][3] SMC-1B belongs to a family of proteins required for chromatid cohesion and DNA recombination during meiosis and mitosis.[3] SMC1ß protein appears to participate with other cohesins REC8, STAG3 and SMC3 in sister-chromatid cohesion throughout the whole meiotic process in human oocytes.[4]

References

  1. "Entrez Gene: structural maintenance of chromosomes 1B".
  2. Dunham I; Shimizu N; Roe BA; Chissoe S; Hunt AR; Collins JE; Bruskiewich R; Beare DM; Clamp M; Smink LJ; Ainscough R; Almeida JP; Babbage A; Bagguley C; Bailey J; Barlow K; Bates KN; Beasley O; Bird CP; Blakey S; Bridgeman AM; Buck D; Burgess J; Burrill WD; O'Brien KP (December 1999). "The DNA sequence of human chromosome 22". Nature. 402 (6761): 489–95. doi:10.1038/990031. PMID 10591208.
  3. 3.0 3.1 Revenkova E; Eijpe M; Heyting C; Gross B; Jessberger R (October 2001). "Novel meiosis-specific isoform of mammalian SMC1". Mol. Cell. Biol. 21 (20): 6984–98. doi:10.1128/MCB.21.20.6984-6998.2001. PMC 99874. PMID 11564881.
  4. Garcia-Cruz R, Brieño MA, Roig I, Grossmann M, Velilla E, Pujol A, Cabero L, Pessarrodona A, Barbero JL, Garcia Caldés M (2010). "Dynamics of cohesin proteins REC8, STAG3, SMC1 beta and SMC3 are consistent with a role in sister chromatid cohesion during meiosis in human oocytes". Hum. Reprod. 25 (9): 2316–27. doi:10.1093/humrep/deq180. PMID 20634189.

Further reading


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