SLCO2A1

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
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View/Edit Human

Solute carrier organic anion transporter family, member 2A1 also known as the prostaglandin transporter (PGT) is a protein that in humans is encoded by the SLCO2A1 gene.[1]

This gene encodes a prostaglandin transporter that is a member of the 12-membrane-spanning organic anion-transporting polypeptide superfamily of transporters. The encoded protein may be involved in mediating the uptake and clearance of prostaglandins in numerous tissues.[1]

Clinical relevance

Mutations in this gene have been shown to cause primary hypertrophic osteoarthropathy.[2]

References

  1. 1.0 1.1 "Entrez Gene: Solute carrier organic anion transporter family, member 2A1". Retrieved 2011-12-30.
  2. Zhang Z, Xia W, He J, Zhang Z, Ke Y, Yue H, Wang C, Zhang H, Gu J, Hu W, Fu W, Hu Y, Li M, Liu Y (January 2012). "Exome sequencing identifies SLCO2A1 mutations as a cause of primary hypertrophic osteoarthropathy". American Journal of Human Genetics. 90 (1): 125–32. doi:10.1016/j.ajhg.2011.11.019. PMID 22197487.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.



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