SLC22A2

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Identifiers
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External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
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RefSeq (protein)

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Solute carrier family 22 member 2 is a protein that in humans is encoded by the SLC22A2 gene.[1][2]

Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. It is found primarily in the kidney, where it may mediate the first step in cation reabsorption.[2]

See also

References

  1. Koehler MR, Wissinger B, Gorboulev V, Koepsell H, Schmid M (Jun 1998). "The two human organic cation transporter genes SLC22A1 and SLC22A2 are located on chromosome 6q26". Cytogenet Cell Genet. 79 (3–4): 198–200. doi:10.1159/000134720. PMID 9605850.
  2. 2.0 2.1 "Entrez Gene: SLC22A2 solute carrier family 22 (organic cation transporter), member 2".

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.



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