Renal compensation

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Renal compensation is a mechanism by which the kidneys can regulate the plasma pH. It is slower than respiratory compensation, but has a greater ability to restore normal values.

Renal compensation in acid-base disorders

See also: Compensatory responses for acid-base disorders

In respiratory acidosis, the kidney produces and excretes ammonium (NH4+) and monophosphate, generating bicarbonate in the process while clearing acid.[1]

In respiratory alkalosis, less HCO3- is reabsorbed, thus lowering the pH.[2]

References


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