RPS15

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
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RefSeq (mRNA)

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RefSeq (protein)

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40S ribosomal protein S15 is a protein that in humans is encoded by the RPS15 gene.[1][2]

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S19P family of ribosomal proteins. It is located in the cytoplasm. This gene has been found to be activated in various tumors, such as insulinomas, esophageal cancers, and colon cancers. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.[2]

References

  1. Shiga K, Yamamoto H, Okamoto H (Jun 1990). "Isolation and characterization of the human homologue of rig and its pseudogenes: the functional gene has features characteristic of housekeeping genes". Proc Natl Acad Sci U S A. 87 (9): 3594–8. doi:10.1073/pnas.87.9.3594. PMC 53948. PMID 2159154.
  2. 2.0 2.1 "Entrez Gene: RPS15 ribosomal protein S15".

Further reading



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