Pyogenic liver abscess pathophysiology

Jump to: navigation, search

Liver abscess Main Page

Pyogenic liver abscess Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating pyogenic liver abscess from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X Ray

CT

MRI

Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Pyogenic liver abscess pathophysiology On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Pyogenic liver abscess pathophysiology

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Pyogenic liver abscess pathophysiology

CDC on Pyogenic liver abscess pathophysiology

Pyogenic liver abscess pathophysiology in the news

Blogs on Pyogenic liver abscess pathophysiology

Directions to Hospitals Treating Type chapter name here

Risk calculators and risk factors for Pyogenic liver abscess pathophysiology

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Yamuna Kondapally, M.B.B.S[2]

Overview

Development of pyogenic liver abscess is the result of infection through the following routes like portal vein (also from pylephlebitis of portal vein), hepatic arteries as metastatic abscesses, direct spread from nearby infection, trauma and retroperitoneal extension from appendix.[1][2][3][4]Ascending biliary infection is the most common source of pyogenic liver abscess.

Pathophysiology

  • Development of pyogenic liver abscess is the result of extension of infection through the following:[1][2][3][4]
  • Ascending biliary infection is the most common source of pyogenic liver abscess.
  • Right lobe of liver is most commonly involved due to its greater blood supply than caudate and left lobes.
  • Bacteria involved in pyogenic liver abscess include:
 
 
 
 
 
 
 
 
 
 
 
Pyogenic liver abscess
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Bacteria
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Gram-positive aerobes
 
 
 
Gram-negative enterics
 
 
 
Anaerobic organisms
 
 
 
Acid fast bacilli
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Streptococcus sp
Staphylococcus aureus / Staphylococcus epidermidis
Actinomyces sp
Enterococcus sp
Streptococcus milleri
 
 
 
Escherichia coli
Salmonella typhi
Yersinia enterocolitica
K.pneumonia
Pseudomonas sp
Proteus sp
Eikenella corrodens
Others
 
 
 
Bacteroids sp
Fusobacterium
Anaerobic/ Microaerophilic streptococci
Other anaerobes
 
 
 
Mycobacterium tuberculosis

Pathogenesis

Gross Pathology

Microscopic Pathology

References

  1. 1.0 1.1 Munro JC (1905). "VII. Lymphatic and Hepatic Infections Secondary to Appendicitis". Ann Surg. 42 (5): 692–734. PMC 1425980. PMID 17861705.
  2. 2.0 2.1 Huang CJ, Pitt HA, Lipsett PA, Osterman FA, Lillemoe KD, Cameron JL; et al. (1996). "Pyogenic hepatic abscess. Changing trends over 42 years". Ann Surg. 223 (5): 600–7, discussion 607-9. PMC 1235191. PMID 8651751.
  3. 3.0 3.1 Rahimian J, Wilson T, Oram V, Holzman RS (2004). "Pyogenic liver abscess: recent trends in etiology and mortality". Clin Infect Dis. 39 (11): 1654–9. doi:10.1086/425616. PMID 15578367.
  4. 4.0 4.1 Lam YH, Wong SK, Lee DW, Lau JY, Chan AC, Yiu RY; et al. (1999). "ERCP and pyogenic liver abscess". Gastrointest Endosc. 50 (3): 340–4. doi:10.1053/ge.1999.v50.98065. PMID 10462653.
  5. Stain SC, Yellin AE, Donovan AJ, Brien HW (1991). "Pyogenic liver abscess. Modern treatment". Arch Surg. 126 (8): 991–6. PMID 1863218.
  6. https://librepathology.org/wiki/Liver_pathology Accessed on February 22, 2017
  7. Lublin M, Bartlett DL, Danforth DN, Kauffman H, Gallin JI, Malech HL; et al. (2002). "Hepatic abscess in patients with chronic granulomatous disease". Ann Surg. 235 (3): 383–91. PMC 1422444. PMID 11882760.

Linked-in.jpg