Protein losing enteropathy

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Protein losing enteropathy
ICD-9 579.8
OMIM 226300
DiseasesDB 10811
MedlinePlus 002277
MeSH D011504

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Synonyms and Keywords: protein loss, protein deficiency, GI protein loss, gastrointestinal protein loss, protein-losing gastroenteropathy, protein losing gastroenteropathy, gastroenteropathy, gastric protein loss, Helicobacter pylori, H pylori, giant hypertrophic gastropathy, Menetrier disease, Ménétrier, disease, loss of plasma proteins from the gastrointestinal tract, excessive leakage of plasma proteins into the lumen of the gastrointestinal tract, lymphatic obstruction, mucosal disease with erosions, ulcerations, swelling of the legs, peripheral edema, decreased plasma oncotic pressure

Overview

Protein losing enteropathy is the loss of plasma proteins from the gastrointestinal tract caused by an array of abnormalities

Presentation

The condition may manifest itself with complications related to protein loss, including edema, or retention of fluid, and ascites, or retention of fluid in the abdomen. Proteins are absorbed in the small bowel, and any condition that affects the digestion or absorption of protein can result in protein losing enteropathy.

Common Causes

Common causes of protein losing enteropathy include celiac disease, Crohn's disease, short bowel syndrome (where the absorptive area for proteins is decreased), intestinal lymphangiectasia, amyloidosis, enteropathy caused by NSAIDs, and giardiasis.

Complete Differential Diagnosis Of Underlying Causes

Diagnosis

The diagnosis of protein losing enteropathy is typically made by excluding other causes of protein loss, such as nephrotic syndrome. Endoscopy and barium imaging can be used to localize the cause of the protein loss in the bowel.

Treatment

Treatment depends upon the underlying condition.

Cost Effectiveness of Protein losing enteropathy

| group5 = Clinical Trials Involving Protein losing enteropathy | list5 = Ongoing Trials on Protein losing enteropathy at Clinical Trials.govTrial results on Protein losing enteropathyClinical Trials on Protein losing enteropathy at Google


| group6 = Guidelines / Policies / Government Resources (FDA/CDC) Regarding Protein losing enteropathy | list6 = US National Guidelines Clearinghouse on Protein losing enteropathyNICE Guidance on Protein losing enteropathyNHS PRODIGY GuidanceFDA on Protein losing enteropathyCDC on Protein losing enteropathy


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| group9 = Genetics, Pharmacogenomics, and Proteinomics of Protein losing enteropathy | list9 = AND (pharmacogenomics)}} Genetics of Protein losing enteropathyAND (pharmacogenomics)}} Pharmacogenomics of Protein losing enteropathyAND (proteomics)}} Proteomics of Protein losing enteropathy


| group10 = Newstories on Protein losing enteropathy | list10 = Protein losing enteropathy in the newsBe alerted to news on Protein losing enteropathyNews trends on Protein losing enteropathy</small>


| group11 = Commentary on Protein losing enteropathy | list11 = Blogs on Protein losing enteropathy

| group12 = Patient Resources on Protein losing enteropathy | list12 = Patient resources on Protein losing enteropathyDiscussion groups on Protein losing enteropathyPatient Handouts on Protein losing enteropathyDirections to Hospitals Treating Protein losing enteropathyRisk calculators and risk factors for Protein losing enteropathy


| group13 = Healthcare Provider Resources on Protein losing enteropathy | list13 = Symptoms of Protein losing enteropathyCauses & Risk Factors for Protein losing enteropathyDiagnostic studies for Protein losing enteropathyTreatment of Protein losing enteropathy

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| group16 = Business Resources on Protein losing enteropathy | list16 = Protein losing enteropathy in the MarketplacePatents on Protein losing enteropathy

| group17 = Informatics Resources on Protein losing enteropathy | list17 = List of terms related to Protein losing enteropathy


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