Prokineticin receptor

Jump to: navigation, search
prokineticin receptor 1
Identifiers
SymbolPROKR1
Alt. symbolsGPR73
Entrez10887
HUGO4524
OMIM607122
RefSeqNM_138964
UniProtQ8TCW9
Other data
LocusChr. 2 p14
prokineticin receptor 2
Identifiers
SymbolPROKR2
Alt. symbolsGPR73L1
Entrez128674
HUGO15836
OMIM607123
RefSeqNM_144773
UniProtQ8NFJ6
Other data
LocusChr. 20 p12.3

The prokineticin receptor is a G protein-coupled receptor which binds the peptide hormone prokineticin. There are two variants each encoded by a different gene (PROKR1, PROKR2).[1] These receptors mediate gastrointestinal smooth muscle contraction and angiogenesis.

References

  1. Lin DC, Bullock CM, Ehlert FJ, Chen JL, Tian H, Zhou QY (2002). "Identification and molecular characterization of two closely related G protein-coupled receptors activated by prokineticins/endocrine gland vascular endothelial growth factor". J. Biol. Chem. 277 (22): 19276–80. doi:10.1074/jbc.M202139200. PMID 11886876.

External links


Linked-in.jpg