Proglumetacin

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Proglumetacin
Proglumetacin.png
Clinical data
ATC code
Pharmacokinetic data
MetabolismHepatic. Undergoes enterohepatic recirculation
Identifiers
CAS Number
PubChem CID
E number{{#property:P628}}
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Chemical and physical data
FormulaC46H58ClN5O8
Molar mass844.43442 g/mol

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Proglumetacin (usually as the maleate salt, trade names Afloxan, Protaxon and Proxil) is a non-steroidal anti-inflammatory drug. It is metabolized in the body to indometacin and proglumide,[1] a drug with antisecretory effects that helps prevent injury to the stomach lining.

References

  1. Setnikar I, Arigoni R, Chisté R, Makovec F, Revel L (1987). "Plasma levels of proglumetacin and its metabolites after intravenous or oral administration in the dog". Arzneimittel-Forschung. 37 (6): 698–702. PMID 3663267.

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