Precursor mRNA

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Overview

Precursor mRNA, more correctly termed heterogeneous nuclear RNA (hnRNA), is an immature single strand of messenger ribonucleic acid (mRNA). HnRNA is synthesized from a DNA template in the cell nucleus by a process called transcription.

Once hnRNA has been completely processed, it is termed "mature messenger RNA", "mature mRNA", or simply "mRNA".

Processing

Eukaryotic hnRNA exists only briefly before it is fully processed into mRNA. HnRNAs include two different types of segments, exons and introns. Exons are segments that are retained in the final mRNA, while introns are removed in a process called splicing, which is performed by the spliceosome.

Additional processing steps attach modifications to the 5' and 3' ends of the hnRNA. These include a 5' cap of 7-methylguanosine and a poly-A tail.

When an hnRNA strand has been properly processed, becoming an mRNA sequence, it is exported out of the nucleus and eventually translated into a protein... a process accomplished in conjunction with ribosomes.

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Cost Effectiveness of Precursor mRNA

| group5 = Clinical Trials Involving Precursor mRNA | list5 = Ongoing Trials on Precursor mRNA at Clinical Trials.govTrial results on Precursor mRNAClinical Trials on Precursor mRNA at Google


| group6 = Guidelines / Policies / Government Resources (FDA/CDC) Regarding Precursor mRNA | list6 = US National Guidelines Clearinghouse on Precursor mRNANICE Guidance on Precursor mRNANHS PRODIGY GuidanceFDA on Precursor mRNACDC on Precursor mRNA


| group7 = Textbook Information on Precursor mRNA | list7 = Books and Textbook Information on Precursor mRNA


| group8 = Pharmacology Resources on Precursor mRNA | list8 = AND (Dose)}} Dosing of Precursor mRNAAND (drug interactions)}} Drug interactions with Precursor mRNAAND (side effects)}} Side effects of Precursor mRNAAND (Allergy)}} Allergic reactions to Precursor mRNAAND (overdose)}} Overdose information on Precursor mRNAAND (carcinogenicity)}} Carcinogenicity information on Precursor mRNAAND (pregnancy)}} Precursor mRNA in pregnancyAND (pharmacokinetics)}} Pharmacokinetics of Precursor mRNA


| group9 = Genetics, Pharmacogenomics, and Proteinomics of Precursor mRNA | list9 = AND (pharmacogenomics)}} Genetics of Precursor mRNAAND (pharmacogenomics)}} Pharmacogenomics of Precursor mRNAAND (proteomics)}} Proteomics of Precursor mRNA


| group10 = Newstories on Precursor mRNA | list10 = Precursor mRNA in the newsBe alerted to news on Precursor mRNANews trends on Precursor mRNA


| group11 = Commentary on Precursor mRNA | list11 = Blogs on Precursor mRNA

| group12 = Patient Resources on Precursor mRNA | list12 = Patient resources on Precursor mRNADiscussion groups on Precursor mRNAPatient Handouts on Precursor mRNADirections to Hospitals Treating Precursor mRNARisk calculators and risk factors for Precursor mRNA


| group13 = Healthcare Provider Resources on Precursor mRNA | list13 = Symptoms of Precursor mRNACauses & Risk Factors for Precursor mRNADiagnostic studies for Precursor mRNATreatment of Precursor mRNA

| group14 = Continuing Medical Education (CME) Programs on Precursor mRNA | list14 = CME Programs on Precursor mRNA

| group15 = International Resources on Precursor mRNA | list15 = Precursor mRNA en EspanolPrecursor mRNA en Francais

| group16 = Business Resources on Precursor mRNA | list16 = Precursor mRNA in the MarketplacePatents on Precursor mRNA

| group17 = Informatics Resources on Precursor mRNA | list17 = List of terms related to Precursor mRNA


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