Plasminogen activator inhibitor-2

Jump to: navigation, search
serpin peptidase inhibitor, clade B (ovalbumin), member 2
Identifiers
Symbol SERPINB2
Alt. Symbols PLANH2, PAI2
Entrez 5055
HUGO 8584
OMIM 173390
RefSeq NM_002575
UniProt P05120
Other data
Locus Chr. 18 q21.3

WikiDoc Resources for Plasminogen activator inhibitor-2

Articles

Most recent articles on Plasminogen activator inhibitor-2

Most cited articles on Plasminogen activator inhibitor-2

Review articles on Plasminogen activator inhibitor-2

Articles on Plasminogen activator inhibitor-2 in N Eng J Med, Lancet, BMJ

Media

Powerpoint slides on Plasminogen activator inhibitor-2

Images of Plasminogen activator inhibitor-2

Photos of Plasminogen activator inhibitor-2

Podcasts & MP3s on Plasminogen activator inhibitor-2

Videos on Plasminogen activator inhibitor-2

Evidence Based Medicine

Cochrane Collaboration on Plasminogen activator inhibitor-2

Bandolier on Plasminogen activator inhibitor-2

TRIP on Plasminogen activator inhibitor-2

Clinical Trials

Ongoing Trials on Plasminogen activator inhibitor-2 at Clinical Trials.gov

Trial results on Plasminogen activator inhibitor-2

Clinical Trials on Plasminogen activator inhibitor-2 at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Plasminogen activator inhibitor-2

NICE Guidance on Plasminogen activator inhibitor-2

NHS PRODIGY Guidance

FDA on Plasminogen activator inhibitor-2

CDC on Plasminogen activator inhibitor-2

Books

Books on Plasminogen activator inhibitor-2

News

Plasminogen activator inhibitor-2 in the news

Be alerted to news on Plasminogen activator inhibitor-2

News trends on Plasminogen activator inhibitor-2

Commentary

Blogs on Plasminogen activator inhibitor-2

Definitions

Definitions of Plasminogen activator inhibitor-2

Patient Resources / Community

Patient resources on Plasminogen activator inhibitor-2

Discussion groups on Plasminogen activator inhibitor-2

Patient Handouts on Plasminogen activator inhibitor-2

Directions to Hospitals Treating Plasminogen activator inhibitor-2

Risk calculators and risk factors for Plasminogen activator inhibitor-2

Healthcare Provider Resources

Symptoms of Plasminogen activator inhibitor-2

Causes & Risk Factors for Plasminogen activator inhibitor-2

Diagnostic studies for Plasminogen activator inhibitor-2

Treatment of Plasminogen activator inhibitor-2

Continuing Medical Education (CME)

CME Programs on Plasminogen activator inhibitor-2

International

Plasminogen activator inhibitor-2 en Espanol

Plasminogen activator inhibitor-2 en Francais

Business

Plasminogen activator inhibitor-2 in the Marketplace

Patents on Plasminogen activator inhibitor-2

Experimental / Informatics

List of terms related to Plasminogen activator inhibitor-2

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Please Take Over This Page and Apply to be Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us [2] to indicate your interest in serving either as an Editor-In-Chief of the entire topic or as an Associate Editor-In-Chief for a subtopic. Please be sure to attach your CV and or biographical sketch.

Overview

Plasminogen activator inhibitor-2 (placental PAI) is a coagulation factor which inactivates tPA & urokinase. It is present in most cells, especially monocytes/macrophages. PAI-2 exists in two forms, a 60 kDa extracellular glycosylated form and a 43 kDa intracellular form.

Fibrinolysis (simplified). Blue arrows denote stimulation, and red arrows inhibition.

It is only present at detectable quantities in blood during pregnancy, as it is produced by the placenta, and may explain partially the increased rate of thrombosis during pregnancy. The majority of expressed PAI-2 remains unsecreted due to the presence of an inefficient internal signal peptide.

See also

External links

Cost Effectiveness of Plasminogen activator inhibitor-2

| group5 = Clinical Trials Involving Plasminogen activator inhibitor-2 | list5 = Ongoing Trials on Plasminogen activator inhibitor-2 at Clinical Trials.govTrial results on Plasminogen activator inhibitor-2Clinical Trials on Plasminogen activator inhibitor-2 at Google


| group6 = Guidelines / Policies / Government Resources (FDA/CDC) Regarding Plasminogen activator inhibitor-2 | list6 = US National Guidelines Clearinghouse on Plasminogen activator inhibitor-2NICE Guidance on Plasminogen activator inhibitor-2NHS PRODIGY GuidanceFDA on Plasminogen activator inhibitor-2CDC on Plasminogen activator inhibitor-2


| group7 = Textbook Information on Plasminogen activator inhibitor-2 | list7 = Books and Textbook Information on Plasminogen activator inhibitor-2


| group8 = Pharmacology Resources on Plasminogen activator inhibitor-2 | list8 = AND (Dose)}} Dosing of Plasminogen activator inhibitor-2AND (drug interactions)}} Drug interactions with Plasminogen activator inhibitor-2AND (side effects)}} Side effects of Plasminogen activator inhibitor-2AND (Allergy)}} Allergic reactions to Plasminogen activator inhibitor-2AND (overdose)}} Overdose information on Plasminogen activator inhibitor-2AND (carcinogenicity)}} Carcinogenicity information on Plasminogen activator inhibitor-2AND (pregnancy)}} Plasminogen activator inhibitor-2 in pregnancyAND (pharmacokinetics)}} Pharmacokinetics of Plasminogen activator inhibitor-2


| group9 = Genetics, Pharmacogenomics, and Proteinomics of Plasminogen activator inhibitor-2 | list9 = AND (pharmacogenomics)}} Genetics of Plasminogen activator inhibitor-2AND (pharmacogenomics)}} Pharmacogenomics of Plasminogen activator inhibitor-2AND (proteomics)}} Proteomics of Plasminogen activator inhibitor-2


| group10 = Newstories on Plasminogen activator inhibitor-2 | list10 = Plasminogen activator inhibitor-2 in the newsBe alerted to news on Plasminogen activator inhibitor-2News trends on Plasminogen activator inhibitor-2</small>


| group11 = Commentary on Plasminogen activator inhibitor-2 | list11 = Blogs on Plasminogen activator inhibitor-2

| group12 = Patient Resources on Plasminogen activator inhibitor-2 | list12 = Patient resources on Plasminogen activator inhibitor-2Discussion groups on Plasminogen activator inhibitor-2Patient Handouts on Plasminogen activator inhibitor-2Directions to Hospitals Treating Plasminogen activator inhibitor-2Risk calculators and risk factors for Plasminogen activator inhibitor-2


| group13 = Healthcare Provider Resources on Plasminogen activator inhibitor-2 | list13 = Symptoms of Plasminogen activator inhibitor-2Causes & Risk Factors for Plasminogen activator inhibitor-2Diagnostic studies for Plasminogen activator inhibitor-2Treatment of Plasminogen activator inhibitor-2

| group14 = Continuing Medical Education (CME) Programs on Plasminogen activator inhibitor-2 | list14 = CME Programs on Plasminogen activator inhibitor-2

| group15 = International Resources on Plasminogen activator inhibitor-2 | list15 = Plasminogen activator inhibitor-2 en EspanolPlasminogen activator inhibitor-2 en Francais

| group16 = Business Resources on Plasminogen activator inhibitor-2 | list16 = Plasminogen activator inhibitor-2 in the MarketplacePatents on Plasminogen activator inhibitor-2

| group17 = Informatics Resources on Plasminogen activator inhibitor-2 | list17 = List of terms related to Plasminogen activator inhibitor-2


}}


Linked-in.jpg