Piperazine

Jump to: navigation, search
Piperazine
Adult Indications & Dosage
Pediatric Indications & Dosage
Contraindications
Warnings & Precautions
Adverse Reactions
Drug Interactions
Use in Specific Populations
Administration & Monitoring
Overdosage
Pharmacology
Clinical Studies
How Supplied
Images
Patient Counseling Information
Precautions with Alcohol
Brand Names
Look-Alike Names

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];

Disclaimer

WikiDoc MAKES NO GUARANTEE OF VALIDITY. WikiDoc is not a professional health care provider, nor is it a suitable replacement for a licensed healthcare provider. WikiDoc is intended to be an educational tool, not a tool for any form of healthcare delivery. The educational content on WikiDoc drug pages is based upon the FDA package insert, National Library of Medicine content and practice guidelines / consensus statements. WikiDoc does not promote the administration of any medication or device that is not consistent with its labeling. Please read our full disclaimer here.

Overview

Piperazine is {{{aOrAn}}} {{{drugClass}}} that is FDA approved for the {{{indicationType}}} of {{{indication}}}. Common adverse reactions include {{{adverseReactions}}}.

Adult Indications and Dosage

FDA-Labeled Indications and Dosage (Adult)

There is limited information regarding Piperazine FDA-Labeled Indications and Dosage (Adult) in the drug label.

Off-Label Use and Dosage (Adult)

Guideline-Supported Use

There is limited information regarding Off-Label Guideline-Supported Use of Piperazine in adult patients.

Non–Guideline-Supported Use

There is limited information regarding Off-Label Non–Guideline-Supported Use of Piperazine in adult patients.

Pediatric Indications and Dosage

FDA-Labeled Indications and Dosage (Pediatric)

There is limited information regarding Piperazine FDA-Labeled Indications and Dosage (Pediatric) in the drug label.

Off-Label Use and Dosage (Pediatric)

Guideline-Supported Use

There is limited information regarding Off-Label Guideline-Supported Use of Piperazine in pediatric patients.

Non–Guideline-Supported Use

There is limited information regarding Off-Label Non–Guideline-Supported Use of Piperazine in pediatric patients.

Contraindications

There is limited information regarding Piperazine Contraindications in the drug label.

Warnings

There is limited information regarding Piperazine Warnings' in the drug label.

Adverse Reactions

Clinical Trials Experience

There is limited information regarding Piperazine Clinical Trials Experience in the drug label.

Postmarketing Experience

There is limited information regarding Piperazine Postmarketing Experience in the drug label.

Drug Interactions

There is limited information regarding Piperazine Drug Interactions in the drug label.

Use in Specific Populations

Pregnancy

Pregnancy Category (FDA): There is no FDA guidance on usage of Piperazine in women who are pregnant.
Pregnancy Category (AUS): There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of Piperazine in women who are pregnant.

Labor and Delivery

There is no FDA guidance on use of Piperazine during labor and delivery.

Nursing Mothers

There is no FDA guidance on the use of Piperazine in women who are nursing.

Pediatric Use

There is no FDA guidance on the use of Piperazine in pediatric settings.

Geriatic Use

There is no FDA guidance on the use of Piperazine in geriatric settings.

Gender

There is no FDA guidance on the use of Piperazine with respect to specific gender populations.

Race

There is no FDA guidance on the use of Piperazine with respect to specific racial populations.

Renal Impairment

There is no FDA guidance on the use of Piperazine in patients with renal impairment.

Hepatic Impairment

There is no FDA guidance on the use of Piperazine in patients with hepatic impairment.

Females of Reproductive Potential and Males

There is no FDA guidance on the use of Piperazine in women of reproductive potentials and males.

Immunocompromised Patients

There is no FDA guidance one the use of Piperazine in patients who are immunocompromised.

Administration and Monitoring

Administration

There is limited information regarding Piperazine Administration in the drug label.

Monitoring

There is limited information regarding Piperazine Monitoring in the drug label.

IV Compatibility

There is limited information regarding the compatibility of Piperazine and IV administrations.

Overdosage

There is limited information regarding Piperazine overdosage. If you suspect drug poisoning or overdose, please contact the National Poison Help hotline (1-800-222-1222) immediately.

Pharmacology

Piperazine
Piperazine structure.jpg
Piperazine3d.png
IUPAC name piperazine
Other names Hexahydropyrazine
Piperazidine
Diethylenediamine
Identifiers
CAS number 110-85-0
PubChem 4837
ATC code P02CB01
SMILES C1CNCCN1
Properties
Molecular formula C4H10N2
Molar mass 86.14 g mol-1
Melting point

106°C

Boiling point

146°C

Acidity (pKa) 5.68, 9.82
Pharmacology
Protein binding 60-70%
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)

Infobox disclaimer and references

Mechanism of Action

There is limited information regarding Piperazine Mechanism of Action in the drug label.

Structure

There is limited information regarding Piperazine Structure in the drug label.

Pharmacodynamics

There is limited information regarding Piperazine Pharmacodynamics in the drug label.

Pharmacokinetics

There is limited information regarding Piperazine Pharmacokinetics in the drug label.

Nonclinical Toxicology

There is limited information regarding Piperazine Nonclinical Toxicology in the drug label.

Clinical Studies

There is limited information regarding Piperazine Clinical Studies in the drug label.

How Supplied

There is limited information regarding Piperazine How Supplied in the drug label.

Storage

There is limited information regarding Piperazine Storage in the drug label.

Images

Drug Images

Package and Label Display Panel

Patient Counseling Information

There is limited information regarding Piperazine Patient Counseling Information in the drug label.

Precautions with Alcohol

Alcohol-Piperazine interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.

Brand Names

There is limited information regarding Piperazine Brand Names in the drug label.

Look-Alike Drug Names

There is limited information regarding Piperazine Look-Alike Drug Names in the drug label.

Drug Shortage Status

Price

References

The contents of this FDA label are provided by the National Library of Medicine.


Linked-in.jpg