Phospholipid:diacylglycerol acyltransferase

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In enzymology, a phospholipid:diacylglycerol acyltransferase (EC 2.3.1.158) is an enzyme that catalyzes the chemical reaction

phospholipid + 1,2-diacylglycerol lysophospholipid + triacylglycerol

Thus, the two substrates of this enzyme are phospholipid and 1,2-diacylglycerol, whereas its two products are lysophospholipid and triacylglycerol.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is phospholipid:1,2-diacyl-sn-glycerol O-acyltransferase. This enzyme is also called PDAT. This enzyme participates in glycerolipid metabolism.

References

  • IUBMB entry for 2.3.1.158
  • BRENDA references for 2.3.1.158 (Recommended.)
  • PubMed references for 2.3.1.158
  • PubMed Central references for 2.3.1.158
  • Google Scholar references for 2.3.1.158
  • Stymne S (2000). "Phospholipid:diacylglycerol acyltransferase: an enzyme that catalyzes the acyl-CoA-independent formation of triacylglycerol in yeast and plants". Proc. Natl. Acad. Sci. U. S. A. 97: 6487&ndash, 92. PMID 10829075.

External links

Gene Ontology (GO) codes


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