Phenylalanine(histidine) transaminase

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In enzymology, a phenylalanine(histidine) transaminase (EC 2.6.1.58) is an enzyme that catalyzes the chemical reaction

L-phenylalanine + pyruvate phenylpyruvate + L-alanine

Thus, the two substrates of this enzyme are L-phenylalanine and pyruvate, whereas its two products are phenylpyruvate and L-alanine.

This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is L-phenylalanine:pyruvate aminotransferase. Other names in common use include phenylalanine (histidine) aminotransferase, phenylalanine(histidine):pyruvate aminotransferase, histidine:pyruvate aminotransferase, and L-phenylalanine(L-histidine):pyruvate aminotransferase.

References

  • IUBMB entry for 2.6.1.58
  • BRENDA references for 2.6.1.58 (Recommended.)
  • PubMed references for 2.6.1.58
  • PubMed Central references for 2.6.1.58
  • Google Scholar references for 2.6.1.58
  • Minatogawa Y, Noguchi T, Kido R (1977). "Species distribution and properties of hepatic phenylalanine (histidine):pyruvate aminotransferase". Hoppe. Seylers. Z. Physiol. Chem. 358: 59&ndash, 67. PMID 14070.

External links

The CAS registry number for this enzyme class is 72560-98-6.

Gene Ontology (GO) codes


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