PAH clearance

Jump to: navigation, search

WikiDoc Resources for PAH clearance

Articles

Most recent articles on PAH clearance

Most cited articles on PAH clearance

Review articles on PAH clearance

Articles on PAH clearance in N Eng J Med, Lancet, BMJ

Media

Powerpoint slides on PAH clearance

Images of PAH clearance

Photos of PAH clearance

Podcasts & MP3s on PAH clearance

Videos on PAH clearance

Evidence Based Medicine

Cochrane Collaboration on PAH clearance

Bandolier on PAH clearance

TRIP on PAH clearance

Clinical Trials

Ongoing Trials on PAH clearance at Clinical Trials.gov

Trial results on PAH clearance

Clinical Trials on PAH clearance at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on PAH clearance

NICE Guidance on PAH clearance

NHS PRODIGY Guidance

FDA on PAH clearance

CDC on PAH clearance

Books

Books on PAH clearance

News

PAH clearance in the news

Be alerted to news on PAH clearance

News trends on PAH clearance

Commentary

Blogs on PAH clearance

Definitions

Definitions of PAH clearance

Patient Resources / Community

Patient resources on PAH clearance

Discussion groups on PAH clearance

Patient Handouts on PAH clearance

Directions to Hospitals Treating PAH clearance

Risk calculators and risk factors for PAH clearance

Healthcare Provider Resources

Symptoms of PAH clearance

Causes & Risk Factors for PAH clearance

Diagnostic studies for PAH clearance

Treatment of PAH clearance

Continuing Medical Education (CME)

CME Programs on PAH clearance

International

PAH clearance en Espanol

PAH clearance en Francais

Business

PAH clearance in the Marketplace

Patents on PAH clearance

Experimental / Informatics

List of terms related to PAH clearance

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]


Overview

Para aminohippurate clearance or PAH clearance is a method used in renal physiology to measure renal plasma flow, which, in turn, is a measure of renal function.

The concentration of para aminohippurate (PAH) is measured in one arterial blood sample (PPAH) and one urine sample(UPAH). The urine flow (V) as also measured. Renal perfusion flow is then calculated by:

What in fact is calculated is the effective renal plasma flow (eRPF). However, since the renal extraction ratio of PAH almost equals 1, then eRPF almost equals RPF.

Precision

The renal extraction ratio of PAH is a normal individual is approximately 0.92[1], and thus not exactly 1.0. Thus, this method usually underestimates RPF by approximately 10%. This margin of error is generally acceptable considering the ease with which eRPF is measured.

References

  1. Reubi FC. Glomberular Filtration Rate, Renal Blood Flow and Blood Viscosity during and after Diabetic Coma. Circ. Res. 1953;1;410-413. Available at: http://circres.ahajournals.org/cgi/reprint/1/5/410.pdf. Accessed on: May 2, 2007.

Linked-in.jpg