N-acetyltransferase

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N-acetyltransferase is an enzyme that catalyzes the transfer of acetyl groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.

Examples

  • AANAT is the symbol for the enzyme arylalkylamine N-acetyltransferase and for the gene that encodes it. AANAT is present in animals, bacteria and yeast but in no other living organisms. AANAT belongs to the large superfamily of acetyltransferase enzymes. AANAT is used in organisms to synthesize melatonin from serotonin.

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