Methopholine

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Methopholine
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Clinical data
SynonymsMethopholine
Legal status
Legal status
  • In general: legal
Identifiers
CAS Number
PubChem CID
E number{{#property:P628}}
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Chemical and physical data
FormulaC20H24ClNO2
Molar mass345.87 g/mol

Methopholine is an opioid analgesic drug invented in the 1960s.

Methopholine is an isoquinoline derivative which is not structurally related to most other opioids.[1] It has around the same efficacy as an analgesic as codeine, and was evaluated for the treatment of postoperative pain, but never commercialised.[2][3][4]

Methopholine is legal throughout the world.



References

  1. Feinberg AP, Creese I, Snyder SH. The opiate receptor: a model explaining structure-activity relationships of opiate agonists and antagonists. Proceedings of the National Academy of Sciences U S A. 1976 Nov;73(11):4215-9.
  2. Moore J, Foldes FF, Davidson GM. An evaluation of the efficacy of methopholine for the relief of postoperative pain. American Journal of Medical Sciences. 1962 Sep;244:337-43.
  3. Cass LJ, Frederik WS. Methopholine, A New Analgesic Agent. American Journal of Medical Sciences. 1963 Nov;246:550-7.
  4. Sciorelli G. Plasma levels and renal excretion of unchanged methopholine in man. Experientia. 1967 Nov 15;23(11):934-6.

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