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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]


Mefenorex (Rondimen, Pondinil, Anexate) is a stimulant drug which was used as an appetite suppressant. It is an amphetamine derivative which was developed in the 1970s and used for the treatment of obesity.[1][2] Mefenorex produces amphetamine as a metabolite,[3] and has been withdrawn in many countries despite having only mild stimulant effects and relatively little abuse potential.[4]


  1. Vincendeau MJ. A new regulator of appetite: mefenorex. (French). Bordeaux Medical. 1970 Jul-Aug;3(7):1951-3.
  2. Beyer G, Huth K, Muller GM, Niemoller H, Raisp I, Vorberg G. The treatment of obesity with the appetite curbing agent Mefenorex. (German). Die Medizinische Welt. 1980 Feb;31(8):306-9.
  3. Rendic S, Slavica M, Medic-Saric M. Urinary excretion and metabolism of orally administered mefenorex. European Journal of Drug Metabolism and Pharmacokinetics. 1994 Apr-Jun;19(2):107-17.
  4. Engel J, Kristen G, Schaefer A, von Schlichtegroll A. Mefenorex (Rondimen). Drug and Alcohol Dependence. 1986 Jun;17(2-3):229-34.