Malaria other diagnostic studies

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Usama Talib, BSc, MD [2]

Overview

Malaria is diagnosed by complementing the clinical findings of the patient with malaria-specific diagnostic studies. PCR is being used to help with malaria elimination.[1]

Other Diagnostic Studies

Other diagnostic studies like PCR, are being used to help with malaria elimination.

PCR

Malaria is diagnosed by complementing the clinical findings of the patient with malaria-specific diagnostic studies. PCR has recently been utilized in studies related to malaria.[1]

  • ddPCR is a technology based on water oil emulsion.
  • It has high sensitivity in detecting even minute number of Plasmodium species found in human body.
  • It can detect all human Plasmodium types.
  • It can be used for malaria elimination by the detection of asymptomatic parasites

MALDI TOF MS

Matrix-Assisted Laser Desorption Ionization Time-Of-Flight Mass Spectrometry is useful in the detection of Anopheles species and the status and type of Plasmodium type they are infected with.[2]

References

  1. 1.0 1.1 Srisutham S, Saralamba N, Malleret B, Rénia L, Dondorp AM, Imwong M (2017). "Four human Plasmodium species quantification using droplet digital PCR". PLoS One. 12 (4): e0175771. doi:10.1371/journal.pone.0175771. PMID 28423028.
  2. Laroche M, Almeras L, Pecchi E, Bechah Y, Raoult D, Viola A; et al. (2017). "MALDI-TOF MS as an innovative tool for detection of Plasmodium parasites in Anopheles mosquitoes". Malar J. 16 (1): 5. doi:10.1186/s12936-016-1657-z. PMC 5209920. PMID 28049524.



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