Magnesium gluconate

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Magnesium gluconate
Magnesium gluconate.png
IUPAC name Magnesium bis[(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate]
Identifiers
CAS number 3632-91-5
PubChem 11418570
ATC code A12CC03
SMILES [Mg+2].[O-]C(=O)[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.[O-]C(=O)[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
InChI InChI=InChI=1S/2C6H12O7.Mg/c2*7-1-2(8)3(9)4(10)5(11)6(12)13;/h2*2-5,7-11H,1H2,(H,12,13);/q;;+2/p-2/t2*2-,3-,4+,5-;/m11./s1
Properties
Molecular formula C12H22MgO14
Molar mass 414.6 g mol-1
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Magnesium gluconate is a compound with formula MgC12H22O14. It is the magnesium salt of gluconic acid.

According to scientific research, Magnesium gluconate shows the highest level of bioavailability of any magnesium salt and is recommended as the optimal salt for human supplementation although of the 10 salts studied, all increased Magnesium levels significantly.

It has E number "E580".

Use in Medicine

There are data on the pharmacological properties of magnesium gluconate. Gluconic acid is the initial substrate for the reactions of pentose phosphate path of oxidation of glucose, so it was suggested that it may affect the energy metabolism of mitochondria. In Ukraine, magnesium gluconate, together with potassium gluconate in the drug Rhythmocor is used to treat heart disease. Pilot studies have shown efficacy in various cardiac arrhythmia. Whether these effects are from the influence of gluconic acid on the metabolism of the heart or from the influence of magnesium and potassium on osmotic pressure is unknown.

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